Evidence map›Paper›PMID 36358503›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Modulation of NRF-2 Pathway Contributes to the Therapeutic Effects of

Ramona D'Amico, Roberta Fusco, Marika Cordaro, Livia Interdonato, Rosalia Crupi, Enrico Gugliandolo, Davide Di Paola, Alessio Filippo Peritore, Rosalba Siracusa, Daniela Impellizzeri and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Modulation of TLR4/NFκB Pathways in Autoimmune Myocarditis.Antioxidants (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Background and roles: myosin in autoimmune diseases.Frontiers in cell and developmental biology · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 2 countries.

Ramona D'AmicoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Via F. Stagno D'Alcontres, 98166 Messina, Italy.ORCID 0000-0003-0389-3871
Roberta FuscoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Via F. Stagno D'Alcontres, 98166 Messina, Italy.ORCID 0000-0003-0223-1403
Marika CordaroDepartment of Biomedical, Dental and Morphological and Functional Imaging, University of Messina, Consolare Valeria, 98166 Messina, Italy.ORCID 0000-0002-3980-0043
Livia InterdonatoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Via F. Stagno D'Alcontres, 98166 Messina, Italy.
Rosalia CrupiDepartment of Veterinary Sciences, Annunziata Campus, University of Messina, Viale Annunziata, 98168 Messina, Italy.ORCID 0000-0002-7629-3132
Enrico GugliandoloDepartment of Veterinary Sciences, Annunziata Campus, University of Messina, Viale Annunziata, 98168 Messina, Italy.ORCID 0000-0001-6840-3154
Davide Di PaolaDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Via F. Stagno D'Alcontres, 98166 Messina, Italy.ORCID 0000-0002-7563-9832
Alessio Filippo PeritoreDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Via F. Stagno D'Alcontres, 98166 Messina, Italy.ORCID 0000-0001-8545-990X
Rosalba SiracusaDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Via F. Stagno D'Alcontres, 98166 Messina, Italy.ORCID 0000-0001-7868-2505
Daniela ImpellizzeriDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Via F. Stagno D'Alcontres, 98166 Messina, Italy.ORCID 0000-0001-9492-3161
Salvatore CuzzocreaDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Via F. Stagno D'Alcontres, 98166 Messina, Italy.ORCID 0000-0001-6131-3690
Rosanna Di PaolaDepartment of Veterinary Sciences, Annunziata Campus, University of Messina, Viale Annunziata, 98168 Messina, Italy.ORCID 0000-0001-6725-8581
University of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocarditis is a clinically dangerous disease that can result in death. Oxidative stress as well as inflammatory and immune responses play important roles in the development of myocarditis. Presently, more research has been carried out on anti-inflammatory treatment using natural compounds. The aim was to evaluate the anti-inflammatory and antioxidant effect of

Indexed as

Boswellia gum extractcytokinesimmunityinflammationNRF-2

Identifiers

PMID36358503
PMCPMC9686591
OpenAlexW4307943150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.