Evidence map›Paper›PMID 36358495›Full record

ReviewAntioxidants (Basel, Switzerland)2022

Ferroptosis and Its Potential Role in Glioma: From Molecular Mechanisms to Therapeutic Opportunities.

Yusong Luo, Guopeng Tian, Xiang Fang, Shengwei Bai, Guoqiang Yuan, Yawen Pan

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Archives of medical science : AMS · 2026
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Neuroferroptosis in health and diseases.Nature reviews. Neuroscience · 2025
    Review
  17. Ferroptosis-mediated immune responses in osteoporosis.Journal of orthopaedic translation · 2025
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yusong LuoDepartment of Neurosurgery, Lanzhou University Second Hospital, Lanzhou 730030, China.
Guopeng TianDepartment of Neurosurgery, Lanzhou University Second Hospital, Lanzhou 730030, China.
Xiang FangDepartment of Neurosurgery, Lanzhou University Second Hospital, Lanzhou 730030, China.
Shengwei BaiDepartment of Neurosurgery, Lanzhou University Second Hospital, Lanzhou 730030, China.
Guoqiang YuanDepartment of Neurosurgery, Lanzhou University Second Hospital, Lanzhou 730030, China.
Yawen PanDepartment of Neurosurgery, Lanzhou University Second Hospital, Lanzhou 730030, China.
Lanzhou University · CNLanzhou University Second Hospital · CN

Funding

Guoqiang Yuan 81960541Yawen Pan 82060455
6 · The paper itself

Abstract

Glioma is the most common intracranial malignant tumor, and the current main standard treatment option is a combination of tumor surgical resection, chemotherapy and radiotherapy. Due to the terribly poor five-year survival rate of patients with gliomas and the high recurrence rate of gliomas, some new and efficient therapeutic strategies are expected. Recently, ferroptosis, as a new form of cell death, has played a significant role in the treatment of gliomas. Specifically, studies have revealed key processes of ferroptosis, including iron overload in cells, occurrence of lipid peroxidation, inactivation of cysteine/glutathione antiporter system Xc

Indexed as

ferroptosisgliomalipid peroxidationmolecular mechanismstreatment

Identifiers

PMID36358495
PMCPMC9686959
OpenAlexW4307940231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.