Evidence map›Paper›PMID 36358435›Full record

ArticleBrain sciences2022

Acoustic Stimulation Improves Memory and Reverses the Contribution of Chronic Sleep Deprivation to Pathology in 3xTgAD Mice.

Shunjie Liu, Qingfeng Lei, Yunyun Liu, Xiaofeng Zhang, Zhong Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Shunjie LiuDepartment of Neurology, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, China.
Qingfeng LeiDepartment of Neurology, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, China.
Yunyun LiuDepartment of Neurology, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, China.
Xiaofeng ZhangDepartment of Neurology, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, China.
Zhong LiDepartment of Neurology, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, China.
Sixth Affiliated Hospital of Sun Yat-sen University · CNGuangdong 999 Brain Hospital · CNSun Yat-sen University · CN

Funding

he Key Project of Guangzhou Science and Technology Program, China 202206010142The National Natural Science Foundation of China NSFC 81801046The Natural Science Foundation of Guangdong, China 2018A030313085The Natural Science Foundation of Guangdong Province, China 2020A1515010111
6 · The paper itself

Abstract

Acoustic stimulation during sleep is believed to enhance slow waves, which are critical to memory consolidation. However, clinical trials of acoustic stimulation have yielded mixed results concerning its effectiveness in improving human memory. A few studies have implied that acoustic stimulation ameliorates the pathology of Alzheimer's disease (AD) in mice with normal sleep. Here, we explored the effect of acoustic stimulation on 3xTgAD mice suffering from chronic sleep deprivation, as these data may shed light on the potential use of acoustic stimulation in AD patients with insomnia.

Indexed as

acoustic stimulationAlzheimer’s diseasesleep deprivationspatial memory

Identifiers

PMID36358435
PMCPMC9688064
OpenAlexW4308480436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.