Evidence map›Paper›PMID 36358396›Full record

ArticleBrain sciences2022

The Role of Folate Deficiency as a Potential Risk Factor for Nontraumatic Anterior Spinal Artery Syndrome in an Adolescent Girl.

Chun-Chieh Hu, Yung-Yu Yang, G W Gant Luxton, Yu-Pang Lin, Kuo-Sheng Hung, Chih-Fen Hu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 75% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Chun-Chieh HuDepartment of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.ORCID 0000-0002-8814-6287
Yung-Yu YangDepartment of General Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.ORCID 0000-0002-9428-7692
G W Gant LuxtonDepartment of Molecular and Cellular Biology, University of California-Davis, Davis, CA 95616, USA.ORCID 0000-0002-6180-8906
Yu-Pang LinDepartment of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Kuo-Sheng HungCenter for Precision Medicine and Genomics, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Chih-Fen HuDepartment of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.ORCID 0000-0002-9208-0890
Tri-Service General Hospital · TW

Funding

Tri-Service General Hospital TSGH-D-11039
6 · The paper itself

Abstract

Nontraumatic anterior spinal artery syndrome (ASAS) is an extremely rare clinical condition in pediatric populations with a mostly unknown underlying etiology. Here we discuss the case of a previously healthy 14-year-old girl presenting with sudden onset acute flaccid paralysis to the emergency department. A spinal STIR/DWI MRI revealed hyperintensities extending from cervical vertebrae C3-6, consistent with the diagnosis of ASAS. In order to determine any precipitating causes of ASAS, we also extensively investigated established potential risk factors for ASAS in our patient and noticed that she had a marked folate deficiency requiring folic acid supplementation to prevent future episodes of ASAS as well as to repair the patient's injured spinal cord. Interestingly, the patient did not display elevated levels of homocysteine nor did she possess the three pathogenic

Indexed as

acute flaccid paralysisfolate deficiencynontraumatic anterior spinal artery syndromeyoung stroke

Identifiers

PMID36358396
PMCPMC9688490
OpenAlexW4307948007

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.