Evidence map›Paper›PMID 36358338›Full record

ArticleBiology2022

m6A Methylation Analysis Reveals Networks and Key Genes Underlying the Coarse and Fine Wool Traits in a Full-sib Merino Family.

Guoying Hua, Xue Yang, Yuhao Ma, Tun Li, Jiankui Wang, Xuemei Deng

Open access · goldAbstract read
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Guoying HuaKey Laboratory of Animal Genetics, Breeding, and Reproduction of the Ministry of Agriculture, China & Beijing Key Laboratory of Animal Genetic Improvement, China Agricultural University, Beijing 100193, China.
Xue YangKey Laboratory of Animal Genetics, Breeding, and Reproduction of the Ministry of Agriculture, China & Beijing Key Laboratory of Animal Genetic Improvement, China Agricultural University, Beijing 100193, China.
Yuhao MaKey Laboratory of Animal Genetics, Breeding, and Reproduction of the Ministry of Agriculture, China & Beijing Key Laboratory of Animal Genetic Improvement, China Agricultural University, Beijing 100193, China.
Tun LiKey Laboratory of Animal Genetics, Breeding, and Reproduction of the Ministry of Agriculture, China & Beijing Key Laboratory of Animal Genetic Improvement, China Agricultural University, Beijing 100193, China.
Jiankui WangKey Laboratory of Animal Genetics, Breeding, and Reproduction of the Ministry of Agriculture, China & Beijing Key Laboratory of Animal Genetic Improvement, China Agricultural University, Beijing 100193, China.
Xuemei DengKey Laboratory of Animal Genetics, Breeding, and Reproduction of the Ministry of Agriculture, China & Beijing Key Laboratory of Animal Genetic Improvement, China Agricultural University, Beijing 100193, China.
China Agricultural University · CN

Funding

National Natural Science Foundation of China; National Key R&D Program of China; Major Project for Cultivation Technology of New Varieties of Genetically Modified Organisms of the Ministry of Agriculture 32002145; 2021YFF1000700; 2016ZX08008-001
6 · The paper itself

Abstract

In our study, a set of lambs with coarse wool type all over their bodies were discovered within a full-sib family during an embryo transfer experiment of merino fine wool sheep. The difference between coarse and fine wool traits were studied from the perspective of RNA modification-N6-methyladenosine. A total of 31,153 peaks were collected, including 15,968 peaks in coarse skin samples and 15,185 peaks in fine skin samples. In addition, 7208 genes were differentially m6A methylated, including 4167 upregulated and 3041 downregulated in coarse skin samples. Four key genes (

Indexed as

m6A modificationMeRIP-seqPI3K/AKT pathwaywool follicle

Identifiers

PMID36358338
PMCPMC9687456
OpenAlexW4308723231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.