Evidence map›Paper›PMID 36358236›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Effect of Phorate on the Development of Hyperglycaemia in Mouse and Resistance Genes in Intestinal Microbiota.

Tingting Cao, Yajie Guo, Dan Wang, Zhiyang Liu, Suli Huang, Changfeng Peng, Shaolin Wang, Yang Wang, Qi Lu, Fan Xiao and 6 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Tingting CaoShenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
Yajie GuoThe Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen 518033, China.
Dan WangSchool of Public Health, Southern Medical University, Guangzhou 510515, China.
Zhiyang LiuShenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
Suli HuangShenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
Changfeng PengShenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
Shaolin WangCollege of Veterinary Medicine, China Agricultural University, Beijing 100091, China.ORCID 0000-0003-0866-4584
Yang WangCollege of Veterinary Medicine, China Agricultural University, Beijing 100091, China.
Qi LuShenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
Fan XiaoShenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
Zhaoyi LiangShenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
Sijia ZhengShenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
Jianzhong ShenCollege of Veterinary Medicine, China Agricultural University, Beijing 100091, China.
Yongning WuFood Safety Research Unit (2019RU014), Chinese Academy of Medical Science, NHC Key Laboratory of Food Safety Risk Assessment, China National Center for Food Safety Risk Assessment, Beijing 100021, China.ORCID 0000-0001-6430-1302
Ziquan LvShenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
Yuebin KeShenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.ORCID 0000-0002-6252-0904
Shenzhen Center for Disease Control and Prevention · CNChina Agricultural University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNSouthern Medical University · CNSun Yat-sen University · CN

Funding

National Key R&D Program of China 2019YFC1605104National Science Foundation of China 22193064Sanming Project of Medicine in Shenzhen SZSM202011008Shenzhen Key Medical Discipline Construction Fund SZXK066Shenzhen Science and Technology Program JCYJ20210324124201004
6 · The paper itself

Abstract

Phorate is a systemic, broad-spectrum organophosphorus insecticide. Although it is commonly used worldwide, phorate, like other pesticides, not only causes environmental pollution but also poses serious threats to human and animal health. Herein, we measured the blood glucose concentrations of high-fat-diet-fed mice exposed to various concentrations of phorate (0, 0.005, 0.05, or 0.5 mg/kg); we also assessed the blood glucose concentrations of high-fat-diet-fed mice exposed to phorate; we also assessed the distribution characteristics of the resistance genes in the intestinal microbiota of these mice. We found that 0.005 and 0.5 mg/kg of phorate induced obvious hyperglycaemia in the high-fat-diet-fed mice. Exposure to phorate markedly reduced the abundance of

Indexed as

hyperglycaemiaintestinal microbiotaphorateresistance genes

Identifiers

PMID36358236
PMCPMC9686891
OpenAlexW4308767824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.