Evidence map›Paper›PMID 36358228›Full record

ArticleAntibiotics (Basel, Switzerland)2022

The Effect of Dalbavancin in Moderate to Severe Hidradenitis Suppurativa.

Elisa Molinelli, Claudia Sapigni, Giovanni Marco D'Agostino, Valerio Brisigotti, Giulio Rizzetto, Ivan Bobyr, Oscar Cirioni, Andrea Giacometti, Lucia Brescini, Sara Mazzanti and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Review
  4. Review
  5. Review
  6. Natural and Man-Made Cyclic Peptide-Based Antibiotics.Antibiotics (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Elisa MolinelliDermatological Unit, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60121 Ancona, Italy.
Claudia SapigniDermatological Unit, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60121 Ancona, Italy.
Giovanni Marco D'AgostinoDermatological Unit, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60121 Ancona, Italy.
Valerio BrisigottiDermatological Unit, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60121 Ancona, Italy.
Giulio RizzettoDermatological Unit, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60121 Ancona, Italy.ORCID 0000-0003-0091-4067
Ivan BobyrDermatological Unit, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60121 Ancona, Italy.
Oscar CirioniDermatological Unit, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60121 Ancona, Italy.
Andrea GiacomettiClinic of Infectious Diseases, Department of Biochemical Sciences and Public Health, Polytechnic University of the Marche Region, 60121 Ancona, Italy.
Lucia BresciniClinic of Infectious Diseases, Department of Biochemical Sciences and Public Health, Polytechnic University of the Marche Region, 60121 Ancona, Italy.
Sara MazzantiClinic of Infectious Diseases, Department of Biochemical Sciences and Public Health, Polytechnic University of the Marche Region, 60121 Ancona, Italy.
Annamaria OffidaniDermatological Unit, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60121 Ancona, Italy.
Oriana SimonettiDermatological Unit, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60121 Ancona, Italy.
Marche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by painful nodules, abscesses, and fistulas, localized to the areas of the folds where apocrine glands are present: the armpits, groin, inframammary region, and genital or perineal region. The management is still challenging, and it includes mainly systemic antibiotics, immunosuppressors, and biologic agents. Antibiotics are frequently used in the management of HS for their anti-inflammatory, immunomodulatory, and antimicrobial properties, but no data have been reported regarding the use of dalbavancin in HS. The aim of our practice was to evaluate efficacy, flare, and disease-free survival after dalbavancin therapy in a selected population with HS. We report the experience of the Ancona Dermatology Clinic in treating HS flare-ups with dalbavancin and its rationale for use. Our observation shows that the use of dalbavancin is an effective and well-tolerated treatment for the management of Hurley stage II-III HS; currently, dalbavancin should be considered as a supportive therapy for selected patients.

Indexed as

antibioticsbiologic agentsdalbavancinhidradenitis suppurativatreatment

Identifiers

PMID36358228
PMCPMC9686733
OpenAlexW4308524158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.