ReviewAntibiotics (Basel, Switzerland)2022
Endophytic Fungi as a Source of Antibacterial Compounds-A Focus on Gram-Negative Bacteria.
Review in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 40 citations in OpenAlex.
- Evaluating yeasts as biocontrol agents against pathogenic and spoilage microorganisms in agri-food: action of volatile organic compounds (VOCs).Applied microbiology and biotechnology · 2026Article
- The endophyteFrontiers in microbiology · 2026Article
- Investigating the potential antibacterial, anti-biofilm, wound healing and anti-inflammatory activity of the extract of Aspergillus niger endophyte isolated from cucumber leaves: in vitro and in vivo study.BMC microbiology · 2025Article
- Exploring the Antimicrobial, Antioxidant and Extracellular Enzymatic Activities of Culturable Endophytic Fungi Isolated from the Leaves ofMicroorganisms · 2025Article
- Endophytic fungi isolated from Vietnamese nut grass (Heliyon · 2025Article
- Bioactivity and metabolic profiling of crude extracts from endophytic bacteria linked toHeliyon · 2025Article
- Identification and Assessment of Secondary Metabolites from Three Fungal Endophytes ofMolecules (Basel, Switzerland) · 2024Article
- Antimicrobial Action Mechanisms of Natural Compounds Isolated from Endophytic Microorganisms.Antibiotics (Basel, Switzerland) · 2024Review
- Endophytic fungi ofSaudi journal of biological sciences · 2024Article
- Incorporating omics-based tools into endophytic fungal research.Biotechnology notes (Amsterdam, Netherlands) · 2024Review
- Antimicrobial and Cytotoxic Activities of the Secondary Metabolites of Endophytic Fungi Isolated from the Medicinal PlantAntibiotics (Basel, Switzerland) · 2023Article
- Biocontrol agent of root-knot nematode Meloidogyne javanica and root-rot fungi, Fusarium solani in okra morphological, anatomical characteristics and productivity under greenhouse conditions.Scientific reports · 2023Article
- Differences in the Production of Extracellular Polymeric Substances (EPS) and Other Metabolites ofMetabolites · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Bacterial resistance has become one of the main motives in the worldwide race for undescribed antibacterial agents. The difficulties in the treatment of bacterial infections are a public health issue that increasingly highlights the need for antimicrobial agents. Endophytic microorganisms are a promising alternative in the search for drugs, due to the vast number of metabolites produced with unique characteristics and bioactive potential. This review highlights the importance of endophytic microorganisms as a source of secondary metabolites in the search for active molecules against bacteria of medical importance, with a special focus on gram-negative species. This fact is supported by the findings raised in this review, which brings an arsenal of 166 molecules with characterized chemical structures and their antibacterial activities. In addition, the low cost, ease of maintenance, and optimization-controlled fermentation conditions favor reproducibility in commercial scale. Given their importance, it is necessary to intensify the search for new molecules from endophytic microorganisms, and to increasingly invest in this very promising font.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.