ArticleAntibiotics (Basel, Switzerland)2022
Assessing the Load, Virulence and Antibiotic-Resistant Traits of ESBL/Ampc
Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 15 citations in OpenAlex.
- Antimicrobial Resistance Gene Profiles inPathogens (Basel, Switzerland) · 2026Article
- Antimicrobial resistance of commensal and extended-spectrum ß-lactamase/AmpC-producing Escherichia coli in organic meat chicken farms.Poultry science · 2026Article
- Quantitative microbial risk assessment of extended-spectrum β-lactamase-producingScience in One Health · 2026Article
- Prevalence of ESBL-ProducingPathogens (Basel, Switzerland) · 2025Article
- Antimicrobial Resistance in Chicken Meat: ComparingMicroorganisms · 2025Article
- Amoxicillin Resistance: An In Vivo Study on the Effects of an Approved Formulation on Antibiotic Resistance in Broiler Chickens.Animals : an open access journal from MDPI · 2025Article
- Phenotypic and Genotypic Characterization of ESBL andAntibiotics (Basel, Switzerland) · 2025Article
- Prevalence and Antimicrobial Resistance of ESBLMicroorganisms · 2025Article
- Prevalence and molecular characterization of ESBL-producing Escherichia coli isolated from broiler chicken and their respective farms environment in Malaysia.BMC microbiology · 2024Article
- Antibiotic Resistance and Virulence Gene Patterns Associated with Multi Drug Resistant Avian PathogenicIndian journal of microbiology · 2024Article
- Isolation and Characterization ofMicroorganisms · 2024Article
- Whole genome sequencing analysis of non-O157 Shiga toxin-producingIranian journal of veterinary research · 2024Article
- Article
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
Poultry is the most likely source of livestock-associated Extended Spectrum Beta-Lactamase (ESBL) and plasmid-mediated AmpC (pAmpC)-producing E. coli (EC) for humans. We tested the hypothesis that farming methods have an impact on the load of ESBL/pAmpC-EC in the gut of broilers at slaughter. Isolates (n = 156) of antibiotic-free (AF), organic (O), and conventional (C) animals were characterized for antibiotic susceptibility and antibiotic resistance genes. Thirteen isolates were whole-genome sequenced. The average loads of ESBL/pAmpC-EC in cecal contents were 4.17 Log CFU/g for AF; 2.85 Log CFU/g for O; and 3.88 Log CFU/g for C type (p < 0.001). ESBL/pAmpC-EC isolates showed resistance to antibiotic classes historically used in poultry, including penicillins, tetracyclines, quinolones, and sulfonamides. Isolates from O and AF farms harbored a lower proportion of resistance to antibiotics than isolates from C farms. Among the determinants for ESBL/pAmpC, CTX-M-1 prevailed (42.7%), followed by TEM-type (29%) and SHV (19.8%). Avian pathogenic E. coli (APEC), belonging to ST117 and ST349, were identified in the collection. These data confirm the possible role of a broiler as an ESBL/AmpC EC and APEC reservoir for humans. Overall, our study suggests that antibiotic-free and organic production may contribute to a reduced exposure to ESBL/AmpC EC for the consumer.
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Registered trials
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