Evidence map›Paper›PMID 36358110›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Suboptimal Concentrations of Ceftazidime/Avibactam (CAZ-AVI) May Select for CAZ-AVI Resistance in Extensively Drug-Resistant

Inmaculada Lopez-Montesinos, María Milagro Montero, Sandra Domene-Ochoa, Carla López-Causapé, Daniel Echeverria, Luisa Sorlí, Nuria Campillo, Sonia Luque, Eduardo Padilla, Nuria Prim and 3 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Efficacy of Ceftazidime-avibactam in treating Gram-negative infections: a systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Antibiotic Resistance in Bacterial Pathogens.Antibiotics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Inmaculada Lopez-MontesinosInfectious Diseases Service, Hospital del Mar, 08003 Barcelona, Spain.ORCID 0000-0002-2675-4412
María Milagro MonteroInfectious Diseases Service, Hospital del Mar, 08003 Barcelona, Spain.
Sandra Domene-OchoaInfectious Diseases Service, Hospital del Mar, 08003 Barcelona, Spain.
Carla López-CausapéCIBER of Infectious Diseases (CIBERINFEC CB21/13/00002 and CB21/13/00099), Institute of Health Carlos III, 28029 Madrid, Spain.
Daniel EcheverriaPharmacy Service, Hospital del Mar, 08003 Barcelona, Spain.ORCID 0000-0003-4975-8798
Luisa SorlíInfectious Diseases Service, Hospital del Mar, 08003 Barcelona, Spain.
Nuria CampilloPharmacy Service, Hospital del Mar, 08003 Barcelona, Spain.
Sonia LuqueInfectious Pathology and Antimicrobials Research Group (IPAR), Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), 08003 Barcelona, Spain.
Eduardo PadillaMicrobiology Service, Laboratori de Referència de Catalunya, 08820 Barcelona, Spain.
Nuria PrimMicrobiology Service, Laboratori de Referència de Catalunya, 08820 Barcelona, Spain.
Santiago GrauInfectious Pathology and Antimicrobials Research Group (IPAR), Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), 08003 Barcelona, Spain.ORCID 0000-0002-8428-1836
Antonio OliverCIBER of Infectious Diseases (CIBERINFEC CB21/13/00002 and CB21/13/00099), Institute of Health Carlos III, 28029 Madrid, Spain.
Juan P HorcajadaInfectious Diseases Service, Hospital del Mar, 08003 Barcelona, Spain.ORCID 0000-0001-9873-5459
Instituto de Salud Carlos III · ESUniversitat Pompeu Fabra · ESGeneralitat de Catalunya · ESHospital Del Mar · ESUniversitat Autònoma de Barcelona · ES

Funding

Instituto de Salud Carlos III PI17/00251La Marató TV3 138/U/2018
6 · The paper itself

Abstract

This study correlates in vivo findings in a patient with an extensively drug-resistant (XDR)

Indexed as

ceftazidime/avibactamcontinuous infusionhollow fibermultidrug-resistantPK/PDPseudomonas aeruginosa

Identifiers

PMID36358110
PMCPMC9686790
OpenAlexW4307122366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.