Evidence map›Paper›PMID 36358105›Full record

ArticleMethods and protocols2019

Optimizing Cell-Free Protein Synthesis for Increased Yield and Activity of Colicins.

Xing Jin, Weston Kightlinger, Seok Hoon Hong

Open access · goldAbstract read
In one paragraph

Article in Methods and protocols, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Developing anACS synthetic biology · 2025
    Article
  4. BeyondChemical reviews · 2025
    Review
  5. Article
  6. Article
  7. Optimizing Cell-Free Protein Synthesis for Antimicrobial Protein Production.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  8. Review
  9. Synthesis of an Anti-CD7 Recombinant Immunotoxin Based on PE24 in CHO andInternational journal of molecular sciences · 2022
    Article
  10. Article
  11. Characterizing and Improving pET Vectors for Cell-free Expression.Frontiers in bioengineering and biotechnology · 2022
    Article
  12. EngineeringAIChE journal. American Institute of Chemical Engineers · 2021
    Article
  13. Review
  14. Antibacterial Activity of Bacteriocinogenic CommensalAntibiotics (Basel, Switzerland) · 2020
    Article
  15. Cell-Free Protein Synthesis: A Promising Option for Future Drug Development.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2020
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Xing JinDepartment of Chemical and Biological Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA.ORCID 0000-0002-0345-0491
Weston KightlingerDepartment of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-5264-4866
Seok Hoon HongDepartment of Chemical and Biological Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA.ORCID 0000-0003-2401-6368
Illinois Institute of Technology · USNorthwestern University · US

Funding

Engineering Colicins to Control Antibiotic-Tolerant BacteriaR15AI130988 · NIAID · ILLINOIS INSTITUTE OF TECHNOLOGY · PI HONG, SEOK HOON · 2018 to 2018
$437k
National Institute of Allergy and Infectious Diseases R15AI130988National Science Foundation DGE-1324585NIAID NIH HHS R15 AI130988
6 · The paper itself

Abstract

Colicins are antimicrobial proteins produced by

Indexed as

antimicrobialscell-free protein synthesischaperonescolicins

Identifiers

PMID36358105
PMCPMC6632115
OpenAlexW2940002064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.