ArticleBMC musculoskeletal disorders2022
Greater muscle volume and muscle fat infiltrate in the deep cervical spine extensor muscles (multifidus with semispinalis cervicis) in individuals with chronic idiopathic neck pain compared to age and sex-matched asymptomatic controls: a cross-sectional study.
Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- From neck to abdomen: cervical (C3) muscle quantification as a surrogate to lumbar (L3) sarcopenia assessment in head and neck cancer: systematic review and meta-analysis.Skeletal radiology · 2026Pooled it
- Muscle fat infiltration and its relation with pain intensity, disability, and cervical curvature in individuals with nonspecific neck pain: A systematic review study.PM & R : the journal of injury, function, and rehabilitation · 2026Pooled it
- Level-dependent changes in cervical multifidus composition following anterior cervical discectomy and fusion: bridging quantitative MRI and clinical perspectives.Archives of orthopaedic and trauma surgery · 2026Article
- The effect of a multimodal exercise program on paraspinal muscle morphology and clinical outcomes in chronic low back pain.Isokinetics and exercise science · 2026Article
- Comparison of Neck Muscle Thickness via Ultrasound in Patients with Ankylosing Spondylitis and Healthy Controls.Archives of rheumatology · 2026Article
- Reliability of Sternocleidomastoid Muscle Stiffness Assessment Using Shear-Wave Elastography Under a Standardized Protocol with Novice and Experienced Examiners: An Intra- and Inter-Examiner Reliability Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Preoperative Planning for Cervical Pedicle Screw Placement: Identifying Key Morphological Parameters.Spine surgery and related research · 2025Article
- Article
- Unveiling and Validating a Modified Method to Assess Cervical Sagittal Alignment as an Effective Substitute for Conventional C2-7 Cobb Angle.Clinics in orthopedic surgery · 2025Article
- What is normal age-related thigh muscle composition among 45- to 84-year-old adults from the UK Biobank study.GeroScience · 2025Article
- Biomechanical mechanisms of multidirectional dynamic compensatory muscle fatigue induced by abnormal cervical curvature: a cross-sectional case-control study based on surface electromyography and Cobb angle.Frontiers in sports and active living · 2025Article
- Association between modifiable and nonmodifiable risk factors with paralumbar muscle health in patients with lower back pain.North American Spine Society journal · 2024Article
- MuscleMap: An Open-Source, Community-Supported Consortium for Whole-Body Quantitative MRI of Muscle.Journal of imaging · 2024Review
- Diagnostic Accuracy of Ultrasound Imaging and Shear Wave Elastography to Discriminate Patients with Chronic Neck Pain from Asymptomatic Individuals.Healthcare (Basel, Switzerland) · 2024Article
- Reduced Cervical Muscle Fat Infiltrate Is Associated with Self-Reported Recovery from Chronic Idiopathic Neck Pain Over Six Months: A Magnetic Resonance Imaging Longitudinal Cohort Study.Journal of clinical medicine · 2024Article
- Cervical Multifidus and Longus Colli Ultrasound Differences among Patients with Cervical Disc Bulging, Protrusion and Extrusion and Asymptomatic Controls: A Cross-Sectional Study.Journal of clinical medicine · 2024Article
- Association between fatty infiltration in the cervical multifidus and treatment response following cervical interlaminar epidural steroid injection.The Korean journal of pain · 2023Article
- The association between morphological characteristics of paraspinal muscle and spinal disorders.Annals of medicine · 2023Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
Muscle size and composition (muscle volume and muscle fat infiltrate [MFI]) may provide insight into possible mechanisms underpinning chronic idiopathic neck pain, a common condition with no definitive underlying pathology. In individuals with chronic idiopathic neck pain > 3 months and age- and sex-matched asymptomatic controls, muscle volumes of levator scapulae, multifidus including semispinalis cervicis (MFSS), semispinalis capitis, splenius capitis including splenius cervicis (SCSC), sternocleidomastoid and longus colli from C3 through T1 were quantified from magnetic resonance imaging. Between-group differences were determined using linear mixed models, accounting for side (left or right), muscle, spinal level, sex, age, and body mass index (BMI). Individuals with pain had greater muscle volume (mean difference 76.8mm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.