Evidence map›Paper›PMID 36357503›Full record

ArticleScientific reports2022

An optically-guided cochlear implant sheath for real-time monitoring of electrode insertion into the human cochlea.

Anastasiya Starovoyt, Bryden C Quirk, Tristan Putzeys, Greet Kerckhofs, Johan Nuyts, Jan Wouters, Robert A McLaughlin, Nicolas Verhaert

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. The effect of surgical complexity on hearing preservation during cochlear implantation with sheathed perimodiolar electrodes.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
  3. Review
  4. Article
  5. The State of High-Resolution Imaging of the Human Inner Ear: A Look Into the Black Box.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  6. Imaging theJournal of biomedical optics · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Journal of biomedical optics · 2023
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Anastasiya StarovoytDepartment of Neurosciences, ExpORL, KU Leuven, 3000, Leuven, Belgium. anastasiya.starovoyt@kuleuven.be.
Bryden C QuirkAustralian Research Council Centre of Excellence for Nanoscale BioPhotonics, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, 5005, Australia.
Tristan PutzeysDepartment of Neurosciences, ExpORL, KU Leuven, 3000, Leuven, Belgium.
Greet KerckhofsBiomechanics Laboratory, Institute of Mechanics, Materials, and Civil Engineering, UCLouvain, 1348, Louvain-La-Neuve, Belgium.
Johan NuytsDepartment of Imaging and Pathology, Division of Nuclear Medicine, KU Leuven, 3000, Leuven, Belgium.
Jan WoutersDepartment of Neurosciences, ExpORL, KU Leuven, 3000, Leuven, Belgium.
Robert A McLaughlin *Australian Research Council Centre of Excellence for Nanoscale BioPhotonics, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, 5005, Australia.
Nicolas Verhaert *Department of Neurosciences, ExpORL, KU Leuven, 3000, Leuven, Belgium.
KU Leuven · BEAustralian Research Council · AUPrometheus Research (United States) · USUniversity of Western Australia · AUVIB-KU Leuven Center for Brain & Disease Research · BE

Funding

Australian Global Connections Fund Bridging Grant 511495075Fonds Wetenschappelijk Onderzoek 12Y6919NFonds Wetenschappelijk Onderzoek 1804816NFonds Wetenschappelijk Onderzoek 1S78519N
6 · The paper itself

Abstract

In cochlear implant surgery, insertion of perimodiolar electrode arrays into the scala tympani can be complicated by trauma or even accidental translocation of the electrode array within the cochlea. In patients with partial hearing loss, cochlear trauma can not only negatively affect implant performance, but also reduce residual hearing function. These events have been related to suboptimal positioning of the cochlear implant electrode array with respect to critical cochlear walls of the scala tympani (modiolar wall, osseous spiral lamina and basilar membrane). Currently, the position of the electrode array in relation to these walls cannot be assessed during the insertion and the surgeon depends on tactile feedback, which is unreliable and often comes too late. This study presents an image-guided cochlear implant device with an integrated, fiber-optic imaging probe that provides real-time feedback using optical coherence tomography during insertion into the human cochlea. This novel device enables the surgeon to accurately detect and identify the cochlear walls ahead and to adjust the insertion trajectory, avoiding collision and trauma. The functionality of this prototype has been demonstrated in a series of insertion experiments, conducted by experienced cochlear implant surgeons on fresh-frozen human cadaveric cochleae.

Indexed as

Cochlear ImplantationCochlear ImplantsBasilar MembraneCochleaElectrodes, ImplantedHumansScala Tympani

Identifiers

PMID36357503
PMCPMC9649659
OpenAlexW4309075694

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.