Evidence map›Paper›PMID 36357490›Full record

ArticleScientific reports2022

Cardiorespiratory fitness decreases the odds for subclinical carotid plaques in apolipoprotein e4 homozygotes.

Jose Luis Perez-Lasierra, José A Casajús, Alejandro Gonzalez-Agüero, José Miguel Arbones-Mainar, José A Casasnovas, Martin Laclaustra, Belén Moreno-Franco

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 73% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jose Luis Perez-LasierraDepartment of Physiatry and Nursing, Universidad de Zaragoza, Zaragoza, Spain.
José A CasajúsDepartment of Physiatry and Nursing, Universidad de Zaragoza, Zaragoza, Spain.
Alejandro Gonzalez-AgüeroDepartment of Physiatry and Nursing, Universidad de Zaragoza, Zaragoza, Spain.
José Miguel Arbones-MainarCentro de Investigación Biomédica en Red de Fisiopatología de La Obesidad Y Nutrición (CIBEROBN), Madrid, Spain.
José A CasasnovasInstituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain.
Martin LaclaustraInstituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain.
Belén Moreno-FrancoInstituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain. mbmoreno@unizar.es.
Centro de Investigación Biomédica en Red · ESInstituto de Investigación Sanitaria Aragón · ESUniversidad de Zaragoza · ES

Funding

Ministerio de Educación, Cultura y Deporte FPU16/02539
6 · The paper itself

Abstract

Some studies suggest that being an apolipoprotein e4 (APOE e4) carrier increases the risk of atherosclerosis, and others suggest that cardiorespiratory fitness (CRF) could play a key role in atherosclerotic prevention. Our aim was to analyze the association of APOE e4 with carotid atherosclerosis and the association of CRF with atherosclerosis in APOE e4 carriers. A cross-sectional analysis based on a subsample of 90 participants in the Aragon Workers' Health Study was carried out. Ultrasonography was used to assess the presence of plaques in carotid territory; the submaximal Chester Step Test was used to assess CRF; and behavioral, demographic, anthropometric, and clinical data were obtained by trained personnel during annual medical examinations. APOE e4e4 participants were categorized into Low-CRF (VO

Indexed as

AtherosclerosisCardiorespiratory FitnessCarotid Artery DiseasesPlaque, AtheroscleroticApolipoprotein E4Apolipoproteins ECross-Sectional StudiesGenotypeHomozygoteHumansPolymorphism, GeneticApolipoprotein E4Apolipoproteins E

Identifiers

PMID36357490
PMCPMC9649711
OpenAlexW4308886056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.