ArticleTranslational psychiatry2022
Superior temporal gyrus and cerebellar loops predict nonsuicidal self-injury in major depressive disorder patients by multimodal neuroimaging.
Article in Translational psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Can machine learning predict non-suicidal self-injury? A systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Neural correlates of implicit emotion regulation in mood and anxiety disorders: an fMRI meta-analytic review.Scientific reports · 2025Pooled it
- The Dark and Gloomy Brain: Grey Matter Volume Alterations in Major Depressive Disorder-Fine-Grained Meta-Analyses.Depression and anxiety · 2024Pooled it
- Abnormal Dynamic Functional Connectivity Within the Fronto-Limbic Network Mediates the Association Between Depressive Symptoms and Non-Suicidal Self-Injury in Adolescents.CNS neuroscience & therapeutics · 2026Article
- Network analysis of depression, anxiety, and NSSI symptoms in adolescents: a clinical sample study.BMC psychiatry · 2026Article
- Identifying past-year self-reported suicidality in outpatients with somatic symptom disorder using an interpretable machine-learning model: a multicenter study with an online calculator.BMC psychiatry · 2026Observational
- Structural covariance network in the striatum is modulated by non-suicidal self-injury in adolescents with major depressive disorder.BMC psychiatry · 2025Article
- Nonsuicidal self-injury prediction with pain-processing neural circuits using interpretable graph neural network.Annals of medicine · 2025Article
- The possible effect of inflammation on non-suicidal self-injury in adolescents with depression: a mediator of connectivity within corticostriatal reward circuitry.European child & adolescent psychiatry · 2025Article
- Unveiling the neural signatures of adolescents with non-suicidal self-injury behavior: an fNIRS study.Frontiers in psychiatry · 2025Article
- The association between family function and adolescents' non-suicidal self-injury behaviors-is Chinese culture involved?Frontiers in psychiatry · 2025Article
- Altered dynamic functional connectivity in antagonistic state in first-episode, drug-naïve patients with major depressive disorder.BMC psychiatry · 2024Article
- Pathway from childhood trauma to nonsuicidal self-injury in adolescents with major depressive disorder: the chain-mediated role of psychological resilience and depressive severity.European archives of psychiatry and clinical neuroscience · 2024Article
- Managing Cancer and Living Meaningfully (CALM) alleviates chemotherapy related cognitive impairment (CRCI) in breast cancer survivors: A pilot study based on resting-state fMRI.Cancer medicine · 2023Article
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In major depressive disorder (MDD) patients, nonsuicidal self-injury (NSSI) is a common comorbidity, and it is important to clarify the underlying neurobiology. Here, we investigated the association of NSSI with brain function and structure in MDD patients. A total of 260 MDD patients and 132 healthy controls (HCs) underwent resting-state functional magnetic resonance imaging and three-dimensional T1-weighted structural scans. NSSI behaviour was assessed through interviews. Voxel-based morphometry analysis (VBM), regional homogeneity analysis (ReHo), functional connectome topology properties and network-based statistics were used to detect the differences in neuroimaging characteristics. Finally, the random forest method was used to evaluate whether these factors could predict NSSI in MDD. Compared with HCs, MDD patients with a history of NSSI showed significant right putamen grey matter volume (GMV), right superior orbital frontal cortex ReHo, left pallidum degree centrality, and putamen-centre function network differences. Compared to MDD subjects without NSSI, those with past NSSI showed significant right superior temporal gyrus (STG) GMV, right lingual gyrus ReHo, sigma and global efficiency, and cerebellum-centre function network differences. The right STG GMV and cerebellum-centre function network were more important than other factors in predicting NSSI behaviour in MDD. MDD patients with a history of NSSI have dysregulated spontaneous brain activity and structure in regions related to emotions, pain regulation, and the somatosensory system. Importantly, right STG GMV and cerebellar loops may play important roles in NSSI in MDD patients.
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