Evidence map›Paper›PMID 36356700›Full record

ReviewCurrent problems in cardiology2023

Nationwide Analysis of the Clinical Outcomes of Patients Admitted With COVID-19 Infection With Myocarditis and Racial Disparities in Mortality.

Harmon R Cannon, Aniesh Bobba, Rahul Shekhar, Karthik Gangu, Shazib Sagheer, Prabal Chourasia, Ishan Garg, Hina Shuja, Najam Wasty, Abu Baker Sheikh

Open access · greenAbstract readReview
In one paragraph

Review in Current problems in cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Harmon R CannonDivision of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM.
Aniesh BobbaDepartment of Medicine, John H Stronger Hospital, Cook County, Chicago, IL.
Rahul ShekharDivision of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM.
Karthik GanguDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, KS.
Shazib SagheerDivision of Cardiology, University of New Mexico Health Sciences Center, Albuquerque, NM; Division of Cardiology, Newark Beth Israel Medical Center, Newark, NJ.
Prabal ChourasiaDepartment of Medicine, Washington Hospital, Fredericksburg.
Ishan GargDivision of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM.
Hina ShujaDepartment of Medicine, Karachi Medical and Dental College, Karachi, Pakistan.
Najam WastyDivision of Cardiology, Newark Beth Israel Medical Center, Newark, NJ.
Abu Baker SheikhDivision of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM. Electronic address: absheikh@salud.unm.edu.
University of New Mexico · USNewark Beth Israel Medical Center · USJohn H. Stroger, Jr. Hospital of Cook County · USKarachi Medical and Dental College · PKMary Washington Hospital · USUniversity of Kansas Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus-19 (COVID-19), while primarily a respiratory virus, affects multiple organ systems, including the cardiovascular system. The relationship between COVID-19 and Myocarditis has been well established, but there are limited large-scale studies evaluating outcome of COVID-19 related Myocarditis. Using National Inpatient Sample (NIS) database, we compared patients with Myocarditis with and without COVID-19 infection. The primary outcome was in-hospital mortality. Secondary outcomes were acute kidney injury requiring hemodialysis, vasopressor use, mechanical ventilation, cardiogenic shock, mechanical circulatory support, sudden cardiac arrest, and length of hospitalization. A total of 17,970 patients were included in study; Myocarditis without COVID (n = 11,515, 64%) and Myocarditis with COVID-19 (n = 6,455, 36%). Patients with COVID-19 and Myocarditis had higher in-hospital mortality compared to those with Myocarditis alone (30.7% vs 6.4%, odds ratio 4.8, 95% CI 3.7-6.3, P< 0.001). That cohort also had significantly higher rates of vasopressor use, mechanical ventilation, sudden cardiac arrest, and acute kidney injury requiring hemodialysis. Given the poor outcome seen in COVID-19 related Myocarditis cohort, further work is needed for development of directed therapies for COVID-19-related Myocarditis.

Indexed as

Acute Kidney InjuryCOVID-19MyocarditisDeath, Sudden, CardiacHospitalizationHumans

Identifiers

PMID36356700
PMCPMC9640210
OpenAlexW4308385504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.