Evidence map›Paper›PMID 36356050›Full record

ArticleAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2023

Future-oriented Emotions and Decisions to Receive Genomic Testing Results Among U.S. Adults of African Ancestry.

Arielle S Gillman, Irina A Iles, William M P Klein, Barbara B Biesecker, Katie L Lewis, Leslie G Biesecker, Rebecca A Ferrer

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Arielle S GillmanBasic Biobehavioral and Psychological Sciences Branch, Behavioral Research Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-3511-4978
Irina A IlesOffice of the Associate Director, Behavioral Research Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
William M P KleinOffice of the Associate Director, Behavioral Research Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Barbara B BieseckerResearch Triangle Institute International, Washington, DC, USA.
Katie L LewisCenter for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Leslie G BieseckerCenter for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Rebecca A FerrerBasic Biobehavioral and Psychological Sciences Branch, Behavioral Research Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-1069-9989
National Institutes of Health · USRTI International · US

Funding

NIH HHS HG200387-08
6 · The paper itself

Abstract

backgroundFuture-oriented emotions are associated with consequential health decision-making, including genomic testing decisions. However, little is known about the relative role of various future-oriented emotions in such decisions. Moreover, most research on predictors of decision making regarding genomic testing is conducted with white participants. PURPOSE: This study examined the role of future-oriented emotions in decisions to receive genomic testing results in U.S. individuals of African descent.

methodsWe analyzed cross-sectional survey data from a genomic sequencing cohort (N = 408). All participants identified as African, African-American, or Afro-Caribbean (Mage = 56.3, 74.7% female). Participants completed measures assessing anticipatory affect (worry about genetic testing results), anticipated distress (feeling devastated if genetic testing showed an increased risk for fatal disease), and anticipated regret (regretting a decision not to learn results). Outcomes were intentions for learning actionable, nonactionable, and carrier results.

resultsAnticipated regret was robustly positively associated with intentions to receive actionable (b = 0.28, p < .001), nonactionable (b = 0.39, p < .001), and carrier (b = 0.30, p < .001) results. Anticipated distress was negatively associated with intentions to receive nonactionable results only (b = -0.16, p < .01). Anticipatory negative affect (worry) was not associated with intentions. At higher levels of anticipated regret, anticipated distress was less strongly associated with intentions to receive nonactionable results (b = 0.14, p = .02).

conclusionsOur results highlight the role of future-oriented emotions in genomic testing among participants who are typically underrepresented in genomic testing studies and behavioral medicine broadly. Future work should examine whether interventions targeting future-oriented emotions such as anticipated regret may have clinically meaningful effects in genetic counseling in similar cohorts.

Indexed as

AnxietyEmotionsAdultCross-Sectional StudiesDecision MakingFemaleGenetic TestingGenomicsHumansMaleAffectAnticipated regretFuture-oriented emotionsGenetic testingGenomic testingMedically underserved

Identifiers

PMID36356050
PMCPMC10122098
OpenAlexW4308679224

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.