Evidence map›Paper›PMID 36355974›Full record

ReviewToxins2022

The Contribution of Phospholipase A

Naira Ayvazyan, Gevorg Ghukasyan, Lusine Ghulikyan, Gayane Kirakosyan, Gohar Sevoyan, Armen Voskanyan, Zaruhi Karabekyan

Open access · goldAbstract readReview
In one paragraph

Review in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. International journal of molecular sciences · 2025
    Article
  6. Vipera Snakebite in Children: A Focus on Europe.Children (Basel, Switzerland) · 2025
    Review
  7. Takotsubo cardiomyopathy associated withFrontiers in cardiovascular medicine · 2025
    Article
  8. Article
  9. Article
  10. Pulmonary involvement from animal toxins: the cellular mechanisms.The journal of venomous animals and toxins including tropical diseases · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Naira AyvazyanOrbeli Institute of Physiology, Orbely str. 22, Yerevan 0028, Armenia.ORCID 0000-0002-7588-2277
Gevorg GhukasyanOrbeli Institute of Physiology, Orbely str. 22, Yerevan 0028, Armenia.ORCID 0000-0003-0796-6062
Lusine GhulikyanOrbeli Institute of Physiology, Orbely str. 22, Yerevan 0028, Armenia.
Gayane KirakosyanOrbeli Institute of Physiology, Orbely str. 22, Yerevan 0028, Armenia.
Gohar SevoyanOrbeli Institute of Physiology, Orbely str. 22, Yerevan 0028, Armenia.
Armen VoskanyanOrbeli Institute of Physiology, Orbely str. 22, Yerevan 0028, Armenia.
Zaruhi KarabekyanOrbeli Institute of Physiology, Orbely str. 22, Yerevan 0028, Armenia.
L. A. Orbeli Institute of Physiology NAS RA · AM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing concern about the use of animal models has stimulated the development of in vitro cell culture models for analysis of the biological effects of snake venoms. However, the complexity of animal venoms and the extreme synergy of the venom components during envenomation calls for critical review and analysis. The epithelium is a primary target for injected viper venom's toxic substances, and therefore, is a focus in modern toxinology. We used the Vero epithelial cell line as a model to compare the actions of a crude

Indexed as

ViperidaeViper VenomsAnimalsChlorocebus aethiopsLipid PeroxidationMetalloproteasesPhospholipases A2Reactive Oxygen SpeciesVero CellsMetalloproteasesPhospholipases A2Reactive Oxygen SpeciesViper Venomschemiluminescenceextracellular acidificationmetalloproteinasesoxygen consumptionphospholipase A2snake venom

Identifiers

PMID36355974
PMCPMC9695613
OpenAlexW4307171195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.