ArticleExperimental and clinical psychopharmacology2023
Precision medicine in alcohol use disorder: Mapping etiologic and maintenance mechanisms to mechanisms of behavior change to improve patient outcomes.
Article in Experimental and clinical psychopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Functional magnetic response imaging predictors of alcohol use disorder treatment outcome: a systematic review.Alcohol and alcoholism (Oxford, Oxfordshire) · 2026Pooled it
- Cognitive-behavioral treatment for gambling harm: Umbrella review and meta-analysis.Clinical psychology review · 2023Pooled it
- Multimodal Nutraceutical and Psychological Intervention for GGT Reduction in Individuals with Alcohol Use Disorder.Nutrients · 2026Trial
- Individualized assignment to short-term alcohol abstinence: A proof-of-concept human laboratory study using psychopathology dimensions.Drug and alcohol dependence reports · 2026Article
- Compulsive sexual behavior disorder (CSBD) and problematic pornography use (PPU): A comprehensive, interdisciplinary, and expert-informed narrative review with suggested future directions.Journal of behavioral addictions · 2026Review
- From Assessment to Intervention: Leveraging Ecological Momentary Assessment (EMA) to Develop a Personalized mobile-health (mHealth) Ecological Momentary Intervention (EMI) for Young Adults With ADHD and High-Risk Alcohol Use.Journal of studies on alcohol and drugs · 2026Article
- Alcohol Cues Elicit Differences in Brain Activation Patterns of Abstinent Men and Women with Alcohol Use Disorders.Neuropsychiatric disease and treatment · 2026Article
- The Point-Scoring Reaction-Time Task: Evidence for reliability of sensitivity to reward (but not punishment) and links with alcohol involvement.Experimental and clinical psychopharmacology · 2025Article
- Common and uncommon risky drinking patterns in young adulthood uncovered by person-specific computational modeling.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025Article
- Learning & motivational talk in smoking cessation interventions: An examination of session language in two randomized trials.Patient education and counseling · 2025Article
- Comparing the psychometric properties of reward and relief drinking measures.Experimental and clinical psychopharmacology · 2024Article
- Validation of predicted individual treatment effects in out of sample respondents.Statistics in medicine · 2024Article
- Longitudinal measurement invariance of constructs derived from the addiction cycle.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024Article
- The role of resilience in the relationship between stress and alcohol.Neurobiology of stress · 2024Article
- Examining the validity of the addictions neuroclinical assessment domains in a crowdsourced sample of adults with current alcohol use.Experimental and clinical psychopharmacology · 2024Article
- Beyond mediators: A critical review and methodological path forward for studying mechanisms in alcohol use treatment research.Alcohol, clinical & experimental research · 2024Review
- The mindful resiliency in recovery model: empowering the transcendence of stigma.Frontiers in psychology · 2024Article
- Improving Social Recovery Capital Research To Enhance Clinical Utility: A Proposed Agenda.Addiction research & theory · 2024Article
- Evidence-Based Assessment of Substance Use Disorder.Assessment · 2024Review
- (Mis)understanding alcohol use disorder: Making the case for a public health first approach.Drug and alcohol dependence · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Precision medicine has been advanced as a potential solution to the problem of alcohol use disorder heterogeneity and modest alcohol use disorder treatment efficacy. The success of precision medicine lies in our ability to first identify the etiologic and maintenance mechanisms at play for a given person and then choose the treatment that is most likely to address such mechanisms. There exist several frameworks that describe empirically supported substance use disorder (SUD) etiologic and maintenance mechanisms (e.g., the Etiologic, Theory-based, Ontogenetic, Hierarchical [ETOH] Framework). There also exists a large literature on mechanisms of behavior change in alcohol use disorder treatment. However, the mechanism of behavior change literature on alcohol use disorder treatments has focused broadly on mechanisms of change rather than more specifically on core alcohol use disorder etiologic and maintenance mechanisms. Thus, the two types of mechanisms have never been integrated or systematically evaluated for their overlap. As such, the aim of the present brief review is to demonstrate how commonly used alcohol use disorder treatments may overlap with and directly target certain alcohol use disorder etiologic and maintenance mechanisms (specifically those described by the ETOH framework). We delineate empirically plausible overlapping mechanisms and theoretically plausible overlapping mechanisms that warrant more research. Last, based on the identification of empirically and theoretically plausible overlapping mechanisms, we elaborate on how ongoing work related to alcohol use disorder precision medicine may test specific hypotheses regarding which treatments work best for whom. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.