Evidence map›Paper›PMID 36355560›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Concomitant Administration of Capecitabine and Folate Supplements: Need to Encourage Medication Reconciliation.

Berenice Stefanelli, Carmine Sellitto, Emanuela De Bellis, Martina Torsiello, Nicola Bertini, Angelo Maria Pezzullo, Graziamaria Corbi, Francesco Sabbatino, Stefano Pepe, Angela Tesse and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Folic acid deficiency in cancer therapy: a review of chemotherapy-induced malabsorption and supportive care strategies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Berenice StefanelliPostgraduate School of Clinical Pharmacology and Toxicology, University of Salerno, Via S. Allende, 84081 Baronissi, Italy.ORCID 0000-0002-7986-8704
Carmine SellittoDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Via S. Allende, 84081 Baronissi, Italy.ORCID 0000-0002-5595-7841
Emanuela De BellisPostgraduate School of Clinical Pharmacology and Toxicology, University of Salerno, Via S. Allende, 84081 Baronissi, Italy.ORCID 0000-0002-8543-5462
Martina TorsielloPhD School "Scienze Biochimiche e Biotecnologiche", Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Piazza Luigi Miraglia, 80138 Naples, Italy.
Nicola BertiniPostgraduate School of Clinical Pharmacology and Toxicology, University of Salerno, Via S. Allende, 84081 Baronissi, Italy.
Angelo Maria PezzulloPublic Health Department, Catholic University, Largo Francesco Vito, 00168 Rome, Italy.
Graziamaria CorbiDepartment of Medicine and Health Sciences, University of Molise, 86100 Campobasso, Italy.ORCID 0000-0002-3441-889X
Francesco SabbatinoDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Via S. Allende, 84081 Baronissi, Italy.ORCID 0000-0001-6431-8278
Stefano PepeDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Via S. Allende, 84081 Baronissi, Italy.
Angela TesseUniversité de Nantes, CHU Nantes, CNRS, INSERM, l'Institut du Thorax, CEDEX 01, F-44000 Nantes, France.ORCID 0000-0002-2153-4357
Valeria ContiClinical Pharmacology Unit, San Giovanni di Dio e Ruggi d'Aragona University Hospital, Via San Leonardo 1, 84131 Salerno, Italy.ORCID 0000-0001-6964-2739
Amelia FilippelliClinical Pharmacology Unit, San Giovanni di Dio e Ruggi d'Aragona University Hospital, Via San Leonardo 1, 84131 Salerno, Italy.ORCID 0000-0002-8235-9118
University of Salerno · ITCentre National de la Recherche Scientifique · FRUniversità Cattolica del Sacro Cuore · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Molise · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hand-Foot syndrome (HFS) and diarrhoea are dose-limiting Adverse Drug Reactions (ADRs) of capecitabine-based chemotherapy. Four polymorphisms in the

Indexed as

adverse drug reactionsdiarrhoeafluoropyrimidinesfolic acidhand foot syndrometoxicity

Identifiers

PMID36355560
PMCPMC9693983
OpenAlexW4308771938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.