Evidence map›Paper›PMID 36355491›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Identification of a Novel p53 Modulator Endowed with Antitumoural and Antibacterial Activity through a Scaffold Repurposing Approach.

Elisa Nuti, Valeria La Pietra, Simona Daniele, Doretta Cuffaro, Lidia Ciccone, Chiara Giacomelli, Carolina Cason, Alfonso Carotenuto, Vincenzo Maria D'Amore, Eleonora Da Pozzo and 6 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Elisa NutiDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0003-2669-5376
Valeria La PietraDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.
Simona DanieleDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-7391-3087
Doretta CuffaroDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-8842-542X
Lidia CicconeDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-2762-1929
Chiara GiacomelliDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-6244-602X
Carolina CasonUnit of Advanced Microbiology Diagnosis and Translational Research, Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0002-3456-4395
Alfonso CarotenutoDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0001-7532-5449
Vincenzo Maria D'AmoreDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-6460-3447
Eleonora Da PozzoDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0003-4762-8949
Barbara CostaDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Riccardo Di LeoDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-5051-1584
Manola ComarUnit of Advanced Microbiology Diagnosis and Translational Research, Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.
Luciana MarinelliDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.
Claudia MartiniDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-9379-3027
Armando RosselloDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.
University of Pisa · ITUniversity of Naples Federico II · ITIRCCS Materno Infantile Burlo Garofolo · ITUniversity of Trieste · IT

Funding

Ministry of Education, Universities and Research RBFR10ZJQTUniversity of Pisa 202058
6 · The paper itself

Abstract

Intracellular pathogens, such as

Indexed as

antibacterial activityChlamydia trachomatisglioblastoma multiformep53–MDM2 complexp53 modulatorvirtual screening

Identifiers

PMID36355491
PMCPMC9692514
OpenAlexW4307631416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.