Evidence map›Paper›PMID 36355291›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Techniques for Visualization and Quantification of Primary Cilia in Chondrocytes.

Huan Meng, Clare L Thompson, Clarissa R Coveney, Angus K Wann, Martin M Knight

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Huan MengCentre for Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, London, UK.
Clare L ThompsonCentre for Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, London, UK.
Clarissa R CoveneyKennedy Institute of Rheumatology, Medical Sciences Division, University of Oxford, Oxford, UK.
Angus K WannKennedy Institute of Rheumatology, Medical Sciences Division, University of Oxford, Oxford, UK.
Martin M KnightCentre for Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, London, UK. m.m.knight@qmul.ac.uk.
Queen Mary University of London · GBHarvard University · USUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary cilia regulate and coordinate a variety of cell signaling pathways important in chondrocyte physiology and cartilage development, health, and disease. Despite this, the chondrocyte primary cilium and its associated role in cartilage biology remains poorly understood. Key to elucidating primary cilia structure and function in chondrocytes is the ability to visualize this unique structure. Here we describe materials and methods for immunofluorescence labeling, microscopy, and measurement of chondrocyte primary cilia.

Indexed as

Cartilage, ArticularChondrocytesCiliaSignal TransductionChondrocyteConfocal microscopyImmunofluorescencePrimary ciliaQuantificationSuper resolution

Identifiers

PMID36355291
OpenAlexW4308907357

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.