Evidence map›Paper›PMID 36355255›Full record

ArticleCommunity mental health journal2023

Antipsychotics and Medical Comorbidity: A Retrospective Study in an Urban Outpatient Psychiatry Clinic.

Catherine W Bennett, Lauren Gensler, David R Goldsmith

Abstract read
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In one paragraph

Article in Community mental health journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Catherine W BennettDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive, Suite 331K, Atlanta, GA, 30329, USA. cwbenn2@emory.edu.
Lauren GenslerDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive, Suite 331K, Atlanta, GA, 30329, USA.
David R GoldsmithDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive, Suite 331K, Atlanta, GA, 30329, USA.
Grady Memorial Hospital · USEmory University · US

Funding

Impact of Inflammation on Reward Circuits, Motivational Deficits and Negative Symptoms in SchizophreniaK23MH114037 · NIMH · EMORY UNIVERSITY · PI GOLDSMITH, DAVID RYAN · 2018 to 2022
$957k
NIMH NIH HHS K23 MH114037
6 · The paper itself

Abstract

Patients with psychotic disorders have increased rates of medical comorbidities. In this cross-sectional study, we investigated the relationship between antipsychotics and medical comorbidities among patients with psychotic disorders in an urban psychiatry clinic in Atlanta, Georgia (n = 860). Each antipsychotic group was compared to a group of patients from the same sample who were not on any antipsychotic, and logistic regression models were constructed for each comorbidity. Ziprasidone was associated with diabetes (aOR 2.56, 95% CI 1.03-6.38) and obesity (aOR 3.19, 95% CI 1.37-7.41). Aripiprazole was associated with obesity (aOR 2.39, 95% CI 1.27-4.51). Clozapine was associated with GERD (aOR 3.59, 95% CI 1.11-11.61), movement disorders (aOR 4.44, 95% CI 1.02-19.32), and arrythmias (4.89, 95% CI 1.44-16.64). Two antipsychotics that are considered weight neutral, ziprasidone and aripiprazole, were associated with cardiometabolic comorbidities. This study suggests that research is warranted to study the association between antipsychotics, medical comorbidity, and psychotic symptom burden.

Indexed as

Antipsychotic AgentsAripiprazoleComorbidityCross-Sectional StudiesHumansObesityOutpatientsPiperazinesRetrospective StudiesThiazolesAntipsychotic AgentsAripiprazolePiperazinesThiazolesziprasidoneCardiometabolic disordersClozapineMedical comorbidityPsychotic disordersSubstance use

Identifiers

PMID36355255
OpenAlexW4308685545

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.