Evidence map›Paper›PMID 36355231›Full record

ArticleActa neurochirurgica2023

The importance of preserving the superior hypophyseal artery infundibular branch in craniopharyngioma surgery.

Hiroo Sasaki, Kazuhito Takeuchi, Yuichi Nagata, Kuniaki Tanahashi, Akihiro Mizuno, Hideyuki Harada, Yugo Kishida, Tadashi Watanabe, Tetsuya Nagatani, Ryuta Saito

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Article in Acta neurochirurgica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hiroo SasakiDepartment of Neurosurgery, Nagoya University, 65 Tsurumai-Cho, Showa-Ku, Nagoya, Aichi, Japan. h-sasaki@med.nagoya-u.ac.jp.ORCID 0000-0002-0999-4289
Kazuhito TakeuchiDepartment of Neurosurgery, Nagoya University, 65 Tsurumai-Cho, Showa-Ku, Nagoya, Aichi, Japan.
Yuichi NagataDepartment of Neurosurgery, Nagoya University, 65 Tsurumai-Cho, Showa-Ku, Nagoya, Aichi, Japan.
Kuniaki TanahashiDepartment of Neurosurgery, Nagoya University, 65 Tsurumai-Cho, Showa-Ku, Nagoya, Aichi, Japan.
Akihiro MizunoDepartment of Neurosurgery, Nagoya University, 65 Tsurumai-Cho, Showa-Ku, Nagoya, Aichi, Japan.
Hideyuki HaradaDepartment of Neurosurgery, Nagoya University, 65 Tsurumai-Cho, Showa-Ku, Nagoya, Aichi, Japan.
Yugo KishidaDepartment of Neurosurgery, Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Aichi, Japan.
Tadashi WatanabeDepartment of Neurosurgery, Aichi Medical University, Nagakute, Aichi, Japan.
Tetsuya NagataniDepartment of Neurosurgery, Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Aichi, Japan.
Ryuta SaitoDepartment of Neurosurgery, Nagoya University, 65 Tsurumai-Cho, Showa-Ku, Nagoya, Aichi, Japan.
Nagoya University Hospital · JPJapanese Red Cross Nagoya Daini Hospital · JPAichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePostoperative pituitary dysfunction, a critical problem in the treatment of craniopharyngiomas, can occur even when the pituitary stalk is preserved. We hypothesized that compromise of the primary superior hypophyseal artery (pSHA) might be related to this occurrence.

methodsWe performed a retrospective review of 131 patients with craniopharyngioma who underwent surgery from April 2009 to September 2021. The inclusion criteria were initial surgery, endoscopic transsphenoidal surgery, preoperative normal pituitary function or pituitary dysfunction in one axis, and morphological preservation of the pituitary stalk. The branches of the pSHA consist mainly of the chiasmatic branches (Cb), infundibular branches (Ib), and descending branches (Db). We analyzed the association between postoperative pituitary function and preservation of these branches.

resultsTwenty patients met the criteria. Preoperative anterior pituitary function was normal in 18 patients, and there was isolated growth hormone deficiency in two patients. No patient had preoperative diabetes insipidus (DI). Anterior pituitary function was unchanged postoperatively in eight patients. Of these eight patients, bilateral preservation of pSHA Ib was confirmed in seven patients. Bilateral preservation of pSHA Ib was the only factor associated with preserved anterior pituitary function (p < 0.01). Fifteen patients were free of permanent DI, and the preservation of any given pSHA branch produced no significant difference in the postoperative occurrence of permanent DI.

conclusionsOur study shows that bilateral preservation of pSHA Ib provides favorable postoperative anterior pituitary function in craniopharyngioma surgery; however, such preservation may have little effect on the postoperative occurrence of DI.

Indexed as

CraniopharyngiomaDiabetes InsipidusPituitary NeoplasmsArteriesHumansPituitary GlandPostoperative ComplicationsRetrospective StudiesCraniopharyngiomaPituitary functionPituitary stalkSuperior hypophyseal artery

Identifiers

PMID36355231
OpenAlexW4308682259

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.