Evidence map›Paper›PMID 36355226›Full record

ArticleCellular and molecular neurobiology2023

Hypoxic White Matter Injury and Recovery After Reoxygenation in Adult Mice: Magnetic Resonance Imaging Findings and Histological Studies.

Yanqiu Liu, Hong Qiao, Wenrui Du, Lu Xu, Fengjuan Yuan, Jianzhong Lin, Minglu Li, Lingling Zhu, Shanhua Li, Jiaxing Zhang

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Yanqiu LiuInstitute of Brain Diseases and Cognition, School of Medicine, Xiamen University, Xiamen, 361102, China.ORCID http://orcid.org/0000-0001-5957-7400
Hong QiaoInstitute of Brain Diseases and Cognition, School of Medicine, Xiamen University, Xiamen, 361102, China.ORCID http://orcid.org/0000-0001-9102-0813
Wenrui DuDepartment of Clinical Medicine, School of Medicine, Xiamen University, Xiamen, 361102, China.ORCID http://orcid.org/0000-0003-0160-3949
Lu XuDepartment of Physiology, School of Basic Medical Science, Xiamen Medical College, Xiamen, 361023, China.ORCID http://orcid.org/0000-0002-5904-5495
Fengjuan YuanInstitute of Brain Diseases and Cognition, School of Medicine, Xiamen University, Xiamen, 361102, China.ORCID http://orcid.org/0000-0002-4645-1646
Jianzhong LinDepartment of Radiology, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361004, China.ORCID http://orcid.org/0000-0001-9311-2965
Minglu LiDepartment of Clinical Medicine, School of Medicine, Xiamen University, Xiamen, 361102, China.ORCID http://orcid.org/0000-0002-0840-198X
Lingling ZhuBeijing Institute of Basic Medical Sciences, Beijing, 100850, China. zhull@bmi.ac.cn.ORCID http://orcid.org/0000-0002-4929-7103
Shanhua LiInstitute of Brain Diseases and Cognition, School of Medicine, Xiamen University, Xiamen, 361102, China. lish@xmu.edu.cn.ORCID http://orcid.org/0000-0003-4390-5558
Jiaxing ZhangInstitute of Brain Diseases and Cognition, School of Medicine, Xiamen University, Xiamen, 361102, China. zhangjiaxing@xmu.edu.cn.ORCID http://orcid.org/0000-0003-0452-1885
Xiamen University · CNBeijing Institute of Education · CNXiamen Medical CollegeZhongshan Hospital of Xiamen University · CN

Funding

National Natural Science Foundation of China 81871519
6 · The paper itself

Abstract

Cognitive dysfunction and brain white matter (WM) injury have been found in adults exposed to hypoxia. However, the mechanisms underlying these impairments remain unclear, and moreover, it is also unclear whether these impairments are reversible after reoxygenation. In this study, adult male mice were exposed to hypoxia for 15 days at a simulated altitude of 4300 m and then reoxygenated for 2 months. Control mice were raised under normoxic conditions. Mice showed a significant decrease in arterial oxygen saturation (SaO

Indexed as

Brain InjuriesWhite MatterAnimalsBrainHypoxiaMagnetic Resonance ImagingMaleMiceFAHypoxiaMyelinOPCs differentiationReoxygenationWM

Identifiers

PMID36355226
PMCPMC11412187
OpenAlexW4308682263

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.