Evidence map›Paper›PMID 36355180›Full record

ArticleViral immunology2023

Surrogate Biomarkers of Disease Progression in Human Pegivirus Seropositive Human Immunodeficiency Virus-Infected Individuals.

Jaisheela Vimali, Yean K Yong, Amudhan Murugesan, Rajeev Ashwin, Pachamuthu Balakrishnan, Sivadoss Raju, Vijayakumar Velu, Marie Larsson, Esaki M Shankar

Open access · greenAbstract read
In one paragraph

Article in Viral immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 4 countries.

Jaisheela VimaliInfection Biology, Department of Biotechnology, Central University of Tamil Nadu, Thiruvarur, India.
Yean K YongLaboratory Centre, Xiamen University Malaysia, Sepang, Selangor, Malaysia.
Amudhan MurugesanVirus Research Diagnostic Laboratory, Department of Microbiology, Government Theni Medical College and Hospital, Theni, India.ORCID 0000-0003-4713-2927
Rajeev AshwinInfection Biology, Department of Biotechnology, Central University of Tamil Nadu, Thiruvarur, India.
Pachamuthu BalakrishnanDepartment of Microbiology, Centre for Infectious Diseases, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, India.
Sivadoss RajuState Public Health Laboratory, Directorate of Public Health and Preventive Medicine, DMS Campus, Chennai, India.
Vijayakumar VeluDivision of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.
Marie LarssonDivision of Molecular Medicine and Virology, Department of Biomedicine and Clinical Sciences, Linköping University, Linköping, Sweden.
Esaki M ShankarInfection Biology, Department of Biotechnology, Central University of Tamil Nadu, Thiruvarur, India.ORCID 0000-0002-7866-9818
Central University of Tamil Nadu · INEmory University · USGovernment Medical College · INGovernment of Tamil Nadu · INLinköping University · SESaveetha University · INXiamen University Malaysia · MY

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
NIAID NIH HHS P30 AI050409NIH HHS P51 OD011132
6 · The paper itself

Abstract

Scientific observations indicate that an actively prevailing systemic condition could alleviate the pathology of another disease. Human pegivirus (HPgV), a highly ubiquitous flavivirus is believed to be associated with slow human immunodeficiency virus (HIV) disease progression, and has seldom been linked to hepatic pathology. In this study, we investigated whether HPgV seropositivity had any impact on surrogate markers of HIV disease progression in a cohort of HIV-infected HPgV seropositive (

Indexed as

Flaviviridae InfectionsHIV InfectionsBiomarkersDisease ProgressionHIVHumansPegivirusBiomarkerscytokinesHIVHPgVliver enzymesplasma viral load

Identifiers

PMID36355180
PMCPMC10024059
OpenAlexW4308681350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.