Evidence map›Paper›PMID 36355163›Full record

ArticleMetabolites2022

Multi-Omics Investigation into Acute Myocardial Infarction: An Integrative Method Revealing Interconnections amongst the Metabolome, Lipidome, Glycome, and Metallome.

Si Ying Lim, Felicia Li Shea Lim, Inmaculada Criado-Navarro, Xin Hao Yeo, Hiranya Dayal, Sri Dhruti Vemulapalli, Song Jie Seah, Anna Karen Carrasco Laserna, Xiaoxun Yang, Sock Hwee Tan and 2 more

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  8. Immunometabolic chaos in septic shock.Journal of leukocyte biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 2 countries.

Si Ying LimNUS Graduate School's Integrative Sciences & Engineering Programme (ISEP), National University of Singapore, Singapore 119077, Singapore.ORCID 0000-0003-4250-2837
Felicia Li Shea LimDepartment of Chemistry, National University of Singapore, Singapore 117543, Singapore.
Inmaculada Criado-NavarroDepartment of Chemistry, National University of Singapore, Singapore 117543, Singapore.ORCID 0000-0002-7514-9681
Xin Hao YeoDepartment of Chemistry, National University of Singapore, Singapore 117543, Singapore.ORCID 0000-0002-6501-0934
Hiranya DayalDepartment of Chemistry, National University of Singapore, Singapore 117543, Singapore.
Sri Dhruti VemulapalliDepartment of Chemistry, National University of Singapore, Singapore 117543, Singapore.
Song Jie SeahDepartment of Chemistry, National University of Singapore, Singapore 117543, Singapore.
Anna Karen Carrasco LasernaDepartment of Chemistry, National University of Singapore, Singapore 117543, Singapore.
Xiaoxun YangCardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore.
Sock Hwee TanCardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore.
Mark Y ChanCardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore.ORCID 0000-0003-0389-7450
Sam Fong Yau LiNUS Graduate School's Integrative Sciences & Engineering Programme (ISEP), National University of Singapore, Singapore 119077, Singapore.ORCID 0000-0002-2092-9226
National University of Singapore · SG

Funding

Ministry of Education R-143-000-B48-114
6 · The paper itself

Abstract

Acute myocardial infarction (AMI) is a leading cause of mortality and morbidity worldwide. This work aims to investigate the translational potential of a multi-omics study (comprising metabolomics, lipidomics, glycomics, and metallomics) in revealing biomechanistic insights into AMI. Following the N-glycomics and metallomics studies performed by our group previously, untargeted metabolomic and lipidomic profiles were generated and analysed in this work via the use of a simultaneous metabolite/lipid extraction and liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis workflow. The workflow was applied to blood plasma samples from AMI cases (

Indexed as

acute myocardial infarctionglycomicslipidomicsmetabolomicsmetallomicsmulti-omics

Identifiers

PMID36355163
PMCPMC9693522
OpenAlexW4308523009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.