ArticleJournal of cardiovascular development and disease2022
Cardio-Ankle Vascular Index as an Arterial Stiffness Marker Improves the Prediction of Cardiovascular Events in Patients without Cardiovascular Diseases.
Article in Journal of cardiovascular development and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Clinical Significance of Cardio-Ankle Vascular Index in Stage A/B Heart Failure Patients With Type 2 Diabetes Mellitus.Journal of clinical medicine research · 2026Article
- Improved Prediction of Cardiovascular Events Using Serial Cardio-Ankle Vascular Index (CAVI) Measurements: A 10-Year Prospective Cohort Study.Clinical cardiology · 2026Article
- Associations between obesity and arterial stiffness assessed by cardio-ankle vascular index in healthy children and adolescents.Frontiers in cardiovascular medicine · 2025Article
- Aortic pulse wave velocity predicts cardiovascular mortality among middle-aged metabolic syndrome subjects without overt cardiovascular disease.Nutrition & metabolism · 2024Article
- Noninvasive Assessment of Vascular Function: From Physiological Tests to Biomarkers.JACC. Asia · 2024Review
- Predictive value of Systematic Coronary Risk Evaluation 2-Diabetes risk model and arterial stiffness for cardiovascular events in the Asian population with type 2 diabetes mellitus.Journal of diabetes investigation · 2024Article
- Prognostic Value of Cardio-Ankle Vascular Index for Cardiovascular and Kidney Outcomes: Systematic Review and Meta-Analysis.JACC. Advances · 2024Article
- Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio-Vascular-Skeletal Muscle Coupling.Journal of clinical medicine · 2023Article
- New Perspectives and Strategies for the Management of Hypertension.Journal of cardiovascular development and disease · 2023Article
- Vascular Health Promotion Project and Vascular Medicine in China-CCVM2004-2023.Vascular health and risk management · 2023Review
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Authors and funding
6 authors.
Funding
Abstract
Several studies have reported that the cardio-ankle vascular index (CAVI), a non-invasive measurement of arterial stiffness, is associated with the incidence of cardiovascular events. We investigated whether adding CAVI to a risk score improves the prediction of cardiovascular events in the setting of primary prevention. This retrospective observational study included consecutive 554 outpatients with cardiovascular disease risk factors but without known cardiovascular disease (68 ± 9 years, 64% men). The CAVI was measured using the VaSera vascular screening system. Major adverse cardiovascular events (MACE) included cardiovascular death, myocardial infarction, stroke, hospitalization for heart failure, and coronary revascularization. During a median follow-up of 4.3 years, cardiovascular events occurred in 65 patients (11.7%). Multivariate Cox analysis showed that abnormal CAVI (>9.0) was significantly associated with the incidence of MACE (hazard ratio 2.31, 95% confidence interval 1.27−4.18). The addition of CAVI to the Suita score, a conventional risk score for coronary heart disease in Japan, significantly improved the C statics from 0.642 to 0.713 (p = 0.04). In addition to a conventional risk score, CAVI improved the prediction of cardiovascular events in patients with cardiovascular disease risk factors but without known cardiovascular diseases.
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