Evidence map›Paper›PMID 36354725›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Laparoscopic versus Open Total Gastrectomy for Locally Advanced Gastric Cancer: Short and Long-Term Results.

Sara Di Carlo, Leandro Siragusa, Alessia Fassari, Enrico Fiori, Francesca La Rovere, Paolo Izzo, Valeria Usai, Giuseppe Cavallaro, Marzia Franceschilli, Sirvjo Dhimolea and 1 more

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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  6. [Prognostic Value of PCMT1 Expression in Gastric Cancer and Its Regulatory Effect on Spindle Assembly Checkpoints].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Sara Di CarloDepartment of Surgical Sciences, University of Rome "Tor Vergata", Viale Oxford 81, 00133 Rome, Italy.
Leandro SiragusaDepartment of Surgical Sciences, University of Rome "Tor Vergata", Viale Oxford 81, 00133 Rome, Italy.ORCID 0000-0001-9218-1176
Alessia FassariDepartment of Surgery "Pietro Valdoni", Sapienza University of Rome, "Umberto I" University Hospital, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0001-8534-9823
Enrico FioriDepartment of Surgery "Pietro Valdoni", Sapienza University of Rome, "Umberto I" University Hospital, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0002-5171-6127
Francesca La RovereDepartment of Surgery "Pietro Valdoni", Sapienza University of Rome, "Umberto I" University Hospital, Viale del Policlinico 155, 00161 Rome, Italy.
Paolo IzzoDepartment of Surgery "Pietro Valdoni", Sapienza University of Rome, "Umberto I" University Hospital, Viale del Policlinico 155, 00161 Rome, Italy.
Valeria UsaiDepartment of Surgical Sciences, University of Rome "Tor Vergata", Viale Oxford 81, 00133 Rome, Italy.
Giuseppe CavallaroDepartment of Surgery "Pietro Valdoni", Sapienza University of Rome, "Umberto I" University Hospital, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0001-7121-2295
Marzia FranceschilliDepartment of Surgical Sciences, University of Rome "Tor Vergata", Viale Oxford 81, 00133 Rome, Italy.
Sirvjo DhimoleaDepartment of Surgical Sciences, University of Rome "Tor Vergata", Viale Oxford 81, 00133 Rome, Italy.
Simone SibioDepartment of Surgery "Pietro Valdoni", Sapienza University of Rome, "Umberto I" University Hospital, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0002-5694-951X
Policlinico Umberto I · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopic gastrectomy for early gastric cancer is widely accepted and routinely performed. However, it is still debated whether the laparoscopic approach is a valid alternative to open gastrectomy in advanced gastric cancer (AGC). The aim of this study is to compare short-and long-term outcomes of laparoscopic (LG) and open (OG) total gastrectomy with D2 lymphadenectomy in patients with AGC.

methodsA retrospective comparative study was conducted on patients who underwent LG and OG for ACG between January 2015 and December 2021. Primary endpoints were the following: recurrence rate, 3-year disease-free survival, 3-year and 5-year overall survival. Univariate and multivariate analysis was conducted to compare variables influencing outcomes and survival.

resultsNinety-two patients included: fifty-three OG and thirty-nine LG. No difference in morbidity and mortality. LG was associated with lower recurrence rates (OG 22.6% versus LG 12.8%,

conclusionLG for AGC seems to provide satisfactory clinical and oncological outcomes in medium volume centers, improved postoperative results and possibly lower recurrence rates.

Indexed as

LaparoscopyNeoplasms, Second PrimaryStomach NeoplasmsGastrectomyHumansRetrospective StudiesTreatment OutcomeD2 lymphadenectomygastric cancerlaparoscopic gastrectomyopen gastrectomy

Identifiers

PMID36354725
PMCPMC9689079
OpenAlexW4308338527

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.