Evidence map›Paper›PMID 36354614›Full record

ReviewGels (Basel, Switzerland)2022

Peptide-Based Supramolecular Hydrogels as Drug Delivery Agents: Recent Advances.

Carlos B P Oliveira, Valéria Gomes, Paula M T Ferreira, José A Martins, Peter J Jervis

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Self-Assembly of Peptides and Biomolecular Systems Into Functional Nanomaterials.Journal of peptide science : an official publication of the European Peptide Society · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. [Advances in hydrogel drug delivery systems for myocardial infarction treatment].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carlos B P OliveiraCentre of Chemistry, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0002-5340-4151
Valéria GomesCentre of Chemistry, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0003-3633-024X
Paula M T FerreiraCentre of Chemistry, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0002-3279-6731
José A MartinsCentre of Chemistry, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0001-9323-3978
Peter J JervisCentre of Chemistry, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0002-5550-4535

Funding

Fundação para a Ciência e Tecnologia UID/QUI/00686/2019, PTDC/QUI-QOR/29015/2017, POCI-01-0145-FEDER-029015
6 · The paper itself

Abstract

Supramolecular peptide hydrogels have many important applications in biomedicine, including drug delivery applications for the sustained release of therapeutic molecules. Targeted and selective drug administration is often preferential to systemic drug delivery, as it can allow reduced doses and can avoid the toxicity and side-effects caused by off-target binding. New discoveries are continually being reported in this rapidly developing field. In this review, we report the latest developments in supramolecular peptide-based hydrogels for drug delivery, focusing primarily on discoveries that have been reported in the last four years (2018-present). We address clinical points, such as peptide self-assembly and drug release, mechanical properties in drug delivery, peptide functionalization, bioadhesive properties and drug delivery enhancement strategies, drug release profiles, and different hydrogel matrices for anticancer drug loading and release.

Indexed as

biomaterialscancer therapycontrolled releasedrug deliveryhydrogelpeptidesmart materialsstimuli-responsivesupramolecular

Identifiers

PMID36354614
PMCPMC9689023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.