Evidence map›Paper›PMID 36354517›Full record

ArticleBioengineering (Basel, Switzerland)2022

Efficient and Economic Heparin Recovery from Porcine Intestinal Mucosa Using Quaternary Ammonium-Functionalized Silica Gel.

Mahmood Karimi Abdolmaleki, Anushree Das, Devang P Khambhati, Ali Shafiee, Kayli Dimas, Carlo Alberto Velazquez, Seyed Mohammad Davachi, Sima Choubtarash Abardeh

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Mahmood Karimi AbdolmalekiDepartment of Biology and Chemistry, Texas A&M International University, Laredo, TX 78041, USA.ORCID 0000-0002-0815-187X
Anushree DasDepartment of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA.ORCID 0000-0002-6401-9275
Devang P KhambhatiDepartment of Biology and Chemistry, Texas A&M International University, Laredo, TX 78041, USA.ORCID 0000-0003-3588-2536
Ali ShafieeDepartment of Chemistry, Cape Breton University, Sydney, NS B1P 6L2, Canada.ORCID 0000-0001-7154-9138
Kayli DimasDepartment of Biology and Chemistry, Texas A&M International University, Laredo, TX 78041, USA.ORCID 0000-0002-6472-2358
Carlo Alberto VelazquezDepartment of Biology and Chemistry, Texas A&M International University, Laredo, TX 78041, USA.ORCID 0000-0003-3057-0701
Seyed Mohammad DavachiDepartment of Biology and Chemistry, Texas A&M International University, Laredo, TX 78041, USA.ORCID 0000-0001-7002-3708
Sima Choubtarash AbardehDepartment of Plant Protection, Ferdowsi University, Mashhad P.O. Box 9177948974, Iran.
Texas A&M International University · USCape Breton University · CAFerdowsi University of Mashhad · IRUniversity of Cincinnati · US

Funding

Welch Foundation BS-0051
6 · The paper itself

Abstract

Heparin, usually isolated from porcine intestinal mucosa, is an active pharmaceutical ingredient of great material value. Traditionally, diverse types of commercial resins were employed as an adsorbent for heparin retrieval from biological samples. However, more recent years have encouraged the advent of new cost-effective adsorbents to achieve enhanced heparin retrieval. Inexpensive cationic ammonium-functionalized silica gels, monodispersed with larger surface area, porosity, and higher thermal stability, were chosen to evaluate the heparin recovery yield from porcine intestinal mucosa. We demonstrated that higher positively charged and less bulky quaternary modified silica gel (e.g., QDASi) could adsorb ~28% (14.7 mg g

Indexed as

adsorptionamine-functionalized silica gelcationic silica gelheparinkineticquaternary ammonium-functionalized silica gelquaternary ammonium saltthermodynamic

Identifiers

PMID36354517
PMCPMC9687748
OpenAlexW4307122278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.