Evidence map›Paper›PMID 36354512›Full record

ArticleBioengineering (Basel, Switzerland)2022

An Objective and Repeatable Sac Isolation Technique for Comparing Biomechanical Metrics in Abdominal Aortic Aneurysms.

Timothy K Chung, Pete H Gueldner, Trevor M Kickliter, Nathan L Liang, David A Vorp

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Timothy K ChungDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15260, USA.ORCID 0000-0002-5344-0187
Pete H GueldnerDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15260, USA.ORCID 0000-0002-9177-8162
Trevor M KickliterDepartment of Mechanical Engineering and Materials Science, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Nathan L LiangDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.ORCID 0000-0003-2863-4008
David A VorpDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15260, USA.ORCID 0000-0002-6467-2151
University of Pittsburgh · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
A Machine Learning-Based Clinical Decision Support Tool to Predict Abdominal Aortic Aneurysm Prognosis Using Existing Longitudinal DataR21HL156246 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VORP, DAVID ALAN · 2021 to 2022
$236k
National Science Foundation 1747452NCATS NIH HHS UL1 TR001857NHLBI NIH HHS R21 HL156246NIH HHS UL1TR001857
6 · The paper itself

Abstract

(1) Abdominal aortic aneurysm (AAA) biomechanics-based metrics often reported may be over/under-estimated by including non-aneurysmal regions in the analyses, which is typical, rather than isolating the dilated sac region. We demonstrate the utility of a novel sac-isolation algorithm by comparing peak/mean wall stress (PWS, MWS), with/without sac isolation, for AAA that were categorized as stable or unstable in 245 patient CT image sets. (2) 245 patient computed tomography images were collected, segmented, meshed, and had subsequent finite element analysis performed in preparation of our novel sac isolation technique. Sac isolation was initiated by rotating 3D surfaces incrementally, extracting 2D projections, curve fitting a Fourier series, and taking the local extrema as superior/inferior boundaries for the aneurysmal sac. The PWS/MWS were compared pairwise using the entire aneurysm and the isolated sac alone. (3) MWS, not PWS, was significantly different between the sac alone and the entire aneurysm. We found no statistically significant difference in wall stress measures between stable (

Indexed as

abdominal aortic aneurysmbiomechanicsfinite element analysissac isolation

Identifiers

PMID36354512
PMCPMC9687639
OpenAlexW4307122608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.