Evidence map›Paper›PMID 36354503›Full record

ArticleBiosensors2022

Carbon Dots Conjugated Antibody as an Effective FRET-Based Biosensor for Progesterone Hormone Screening.

Disha, Poonam Kumari, Manoj K Patel, Parveen Kumar, Manoj K Nayak

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
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  8. Label-Free Biosensor.Biosensors · 2023
    Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

DishaMaterials Science and Sensor Applications, CSIR-Central Scientific Instruments Organisation (CSIR-CSIO), Sector 30-C, Chandigarh 160030, India.
Poonam KumariMaterials Science and Sensor Applications, CSIR-Central Scientific Instruments Organisation (CSIR-CSIO), Sector 30-C, Chandigarh 160030, India.
Manoj K PatelAcademy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
Parveen KumarExigo Recycling Pvt. Ltd., Noida 201309, India.
Manoj K NayakMaterials Science and Sensor Applications, CSIR-Central Scientific Instruments Organisation (CSIR-CSIO), Sector 30-C, Chandigarh 160030, India.ORCID 0000-0002-1984-425X
Central Scientific Instruments Organisation · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, carbon dots (CDs) were synthesized by a one-step hydrothermal method using citric acid and ethylene diamine, and covalently functionalized with antibodies for the sensing of progesterone hormone. The structural and morphological analysis reveals that the synthesized CDs are of average size (diameter 8-10 nm) and the surface functionalities are confirmed by XPS, XRD and FT-IR. Further graphene oxide (GO) is used as a quencher due to the fluorescence resonance energy transfer (FRET) mechanism, whereas the presence of the analyte progesterone turns on the fluorescence because of displacement of GO from the surface of CDs effectively inhibiting FRET efficiency due to the increased distance between donor and acceptor moieties. The linear curve is obtained with different progesterone concentrations with 13.8 nM detection limits (R

Indexed as

Biosensing TechniquesMetal NanoparticlesAntibodiesCarbonFluorescence Resonance Energy TransferGoldGraphiteImmunoassayProgesteroneSpectroscopy, Fourier Transform InfraredAntibodiesCarbonGoldgraphene oxideGraphiteProgesteronebiorecognitionendocrinefluorescence resonance energy transfer (FRET) bioassayhormonal imbalanceimmunosensorprogesterone

Identifiers

PMID36354503
PMCPMC9688503
OpenAlexW4308868360

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.