Evidence map›Paper›PMID 36354464›Full record

ReviewBiosensors2022

Biosensors for the Detection of Enzymes Based on Aggregation-Induced Emission.

Fengli Gao, Gang Liu, Mingyi Qiao, Yingying Li, Xinyao Yi

Open access · goldAbstract readReview
In one paragraph

Review in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Fengli GaoCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.
Gang LiuCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.
Mingyi QiaoCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.
Yingying LiCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.
Xinyao YiCollege of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China.ORCID 0000-0002-9218-7161
Anyang Normal University · CNCentral South University · CN

Funding

National Natural Science Foundation of China 21705166
6 · The paper itself

Abstract

Enzymes play a critical role in most complex biochemical processes. Some of them can be regarded as biomarkers for disease diagnosis. Taking advantage of aggregation-induced emission (AIE)-based biosensors, a series of fluorogens with AIE characteristics (AIEgens) have been designed and synthesized for the detection and imaging of enzymes. In this work, we summarized the advances in AIEgens-based probes and sensing platforms for the fluorescent detection of enzymes, including proteases, phosphatases, glycosidases, cholinesterases, telomerase and others. The AIEgens involve organic dyes and metal nanoclusters. This work provides valuable references for the design of novel AIE-based sensing platforms.

Indexed as

Biosensing TechniquesFluorescent DyesMetalsFluorescent DyesMetalsaggregation-induced emissionenzymesfluorescent biosensorsmetal nanoclustersorganic dyes

Identifiers

PMID36354464
PMCPMC9688369
OpenAlexW4308125365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.