Evidence map›Paper›PMID 36354462›Full record

ReviewBiosensors2022

Overview on the Design of Magnetically Assisted Electrochemical Biosensors.

Yong Chang, Yanyan Wang, Jingyi Zhang, Yuejiao Xing, Gang Li, Dehua Deng, Lin Liu

Open access · goldAbstract readReview
In one paragraph

Review in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. From conventional to biosensor-based detection ofFood and waterborne parasitology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yong ChangCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.ORCID 0000-0001-7807-9730
Yanyan WangCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.
Jingyi ZhangCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.
Yuejiao XingCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.
Gang LiCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.
Dehua DengCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.
Lin LiuCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.ORCID 0000-0001-7982-6005
Anyang Normal University · CN

Funding

Henan Province Natural Science Foundation 202300410028Program for Innovative Research Team of Science and Technology in the University of Henan Province 21IRTSTHN005the Science and Technology Foundation of Anyang City
6 · The paper itself

Abstract

Electrochemical biosensors generally require the immobilization of recognition elements or capture probes on the electrode surface. This may limit their practical applications due to the complex operation procedure and low repeatability and stability. Magnetically assisted biosensors show remarkable advantages in separation and pre-concentration of targets from complex biological samples. More importantly, magnetically assisted sensing systems show high throughput since the magnetic materials can be produced and preserved on a large scale. In this work, we summarized the design of electrochemical biosensors involving magnetic materials as the platforms for recognition reaction and target conversion. The recognition reactions usually include antigen-antibody, DNA hybridization, and aptamer-target interactions. By conjugating an electroactive probe to biomolecules attached to magnetic materials, the complexes can be accumulated near to an electrode surface with the aid of external magnet field, producing an easily measurable redox current. The redox current can be further enhanced by enzymes, nanomaterials, DNA assemblies, and thermal-cycle or isothermal amplification. In magnetically assisted assays, the magnetic substrates are removed by a magnet after the target conversion, and the signal can be monitored through stimuli-response release of signal reporters, enzymatic production of electroactive species, or target-induced generation of messenger DNA.

Indexed as

Aptamers, NucleotideBiosensing TechniquesDNAElectrochemical TechniquesLimit of DetectionNucleic Acid HybridizationAptamers, NucleotideDNAaptasensorDNA biosensorelectrochemical biosensorhomogeneous assayimmunosensormagnetic particle

Identifiers

PMID36354462
PMCPMC9687741
OpenAlexW4308128584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.