Evidence map›Paper›PMID 36354460›Full record

ArticleBiosensors2022

Chitosan Micro-Membranes with Integrated Gold Nanoparticles as an LSPR-Based Sensing Platform.

Diana I Meira, Manuela Proença, Rita Rebelo, Ana I Barbosa, Marco S Rodrigues, Joel Borges, Filipe Vaz, Rui L Reis, Vitor M Correlo

Abstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Diana I MeiraPhysics Center of Minho and Porto Universities (CF-UM-UP), Campus de Azurém, University of Minho, 4800-058 Guimarães, Portugal.ORCID 0000-0002-6300-9243
Manuela ProençaPhysics Center of Minho and Porto Universities (CF-UM-UP), Campus de Azurém, University of Minho, 4800-058 Guimarães, Portugal.ORCID 0000-0002-3330-7709
Rita Rebelo3 B's Research Group, I3Bs-Research Institute on Biomaterials, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Biodegradables and Biomimetics of University of Minho, AvePark-Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017 Guimarães, Portugal.ORCID 0000-0002-2709-4516
Ana I Barbosa3 B's Research Group, I3Bs-Research Institute on Biomaterials, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Biodegradables and Biomimetics of University of Minho, AvePark-Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017 Guimarães, Portugal.ORCID 0000-0001-7695-5186
Marco S RodriguesPhysics Center of Minho and Porto Universities (CF-UM-UP), Campus de Azurém, University of Minho, 4800-058 Guimarães, Portugal.ORCID 0000-0003-3291-0925
Joel BorgesPhysics Center of Minho and Porto Universities (CF-UM-UP), Campus de Azurém, University of Minho, 4800-058 Guimarães, Portugal.ORCID 0000-0001-7421-6902
Filipe VazPhysics Center of Minho and Porto Universities (CF-UM-UP), Campus de Azurém, University of Minho, 4800-058 Guimarães, Portugal.ORCID 0000-0001-5506-996X
Rui L Reis3 B's Research Group, I3Bs-Research Institute on Biomaterials, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Biodegradables and Biomimetics of University of Minho, AvePark-Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017 Guimarães, Portugal.ORCID 0000-0002-4295-6129
Vitor M Correlo3 B's Research Group, I3Bs-Research Institute on Biomaterials, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Biodegradables and Biomimetics of University of Minho, AvePark-Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017 Guimarães, Portugal.ORCID 0000-0002-5516-7583

Funding

Fundação para a Ciência e Tecnologia EXPL/CTM-REF/0750/2021Fundação para a Ciência e Tecnologia SFRH/BD/137076/2018Fundação para a Ciência e Tecnologia SFRH/BD/143262/2019Fundação para a Ciência e Tecnologia UIDB/04650/2020
6 · The paper itself

Abstract

Currently, there is an increasing need to develop highly sensitive plasmonic sensors able to provide good biocompatibility, flexibility, and optical stability to detect low levels of analytes in biological media. In this study, gold nanoparticles (Au NPs) were dispersed into chitosan membranes by spin coating. It has been demonstrated that these membranes are particularly stable and can be successfully employed as versatile plasmonic platforms for molecular sensing. The optical response of the chitosan/Au NPs interfaces and their capability to sense the medium's refractive index (RI) changes, either in a liquid or gas media, were investigated by high-resolution localized surface plasmon resonance (HR-LSPR) spectroscopy, as a proof of concept for biosensing applications. The results revealed that the lowest polymer concentration (chitosan (0.5%)/Au-NPs membrane) presented the most suitable plasmonic response. An LSPR band redshift was observed as the RI of the surrounding media was incremented, resulting in a sensitivity value of 28 ± 1 nm/RIU. Furthermore, the plasmonic membrane showed an outstanding performance when tested in gaseous atmospheres, being capable of distinguishing inert gases with only a 10

Indexed as

ChitosanMetal NanoparticlesGoldRefractometrySurface Plasmon ResonanceChitosanGoldAu nanoparticleschitosan membranehigh-resolution LSPR spectroscopyoptical sensingplasmonics

Identifiers

PMID36354460
PMCPMC9687842

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.