Evidence map›Paper›PMID 36354454›Full record

ArticleBiosensors2022

Alprazolam Detection Using an Electrochemical Nanobiosensor Based on AuNUs/Fe-Ni@rGO Nanocomposite.

Emadoddin Amin Sadrabadi, Fatemeh Khosravi, Ali Benvidi, Amin Shiralizadeh Dezfuli, Pouria Khashayar, Patricia Khashayar, Mostafa Azimzadeh

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Interpol review of forensic drug chemistry, 2022-2025.Forensic science international. Synergy · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Saliva Lipids May Determine Alprazolam Toxicity: An FTIR Study.Iranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Emadoddin Amin SadrabadiDepartment of Chemistry, Faculty of Science, Yazd University, Yazd 8915818411, Iran.
Fatemeh KhosraviDepartment of Medical Biotechnology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd 8915173143, Iran.
Ali BenvidiDepartment of Chemistry, Faculty of Science, Yazd University, Yazd 8915818411, Iran.
Amin Shiralizadeh DezfuliCenter of Excellence in Electrochemistry, Faculty of Chemistry, University of Tehran, Tehran 1439957131, Iran.ORCID 0000-0001-8628-3010
Pouria KhashayarInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G3 8QP, UK.ORCID 0000-0002-0736-2181
Patricia KhashayarCenter for Microsystem Technology, Imec and Ghent University, 9000 Gent, Belgium.ORCID 0000-0001-7525-8418
Mostafa AzimzadehDepartment of Medical Biotechnology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd 8915173143, Iran.ORCID 0000-0002-0588-8112
Ghent University · BEShahid Sadoughi University of Medical Sciences and Health Services · IRYazd University · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite all the psychological advantages of alprazolam, its long list of toxic properties and interactions has caused concern and highlighted the need for a reliable sensing method. In this study, we developed a simple, highly sensitive electrochemical nanobiosensor to determine the desirable dose of alprazolam, averting the undesirable consequences of overdose. Gold nanourchins (AuNUs) and iron-nickel reduced graphene oxide (Fe-Ni@rGO) were immobilized on a glassy carbon electrode, which was treated beforehand. The electrode surface was characterized using cyclic voltammetry, Fourier transform infrared spectroscopy, scanning electron microscopy/energy-dispersive X-ray spectroscopy, and differential pulse voltammetry. The fabricated sensor showed two linear ranges (4 to 500 µg L

Indexed as

GraphiteNanocompositesAlprazolamElectrochemical TechniquesElectrodesGoldNickelAlprazolamGoldgraphene oxideGraphiteNickelnickel monoxidealprazolamAuNUselectrochemical pretreatmentnanobiosensorrGO

Identifiers

PMID36354454
PMCPMC9687846
OpenAlexW4308120829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.