Evidence map›Paper›PMID 36354375›Full record

ReviewACS nano2022

Natural Piezoelectric Biomaterials: A Biocompatible and Sustainable Building Block for Biomedical Devices.

Ruoxing Wang, Jiajie Sui, Xudong Wang

Open access · greenAbstract readReview
In one paragraph

Review in ACS nano, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 177 citations in OpenAlex.

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  10. Flexible Dielectric Acoustic Resonator Patch for Tissue Regeneration.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ruoxing WangDepartment of Materials Science and Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Jiajie SuiDepartment of Materials Science and Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0001-6580-1886
Xudong WangDepartment of Materials Science and Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0002-9762-6792
University of Wisconsin–Madison · US

Funding

Nanogenerator-Driven Self-Sustainable Power Source for Intracardiac PacemakersR01HL157077 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI WANG, XUDONG · 2021 to 2024
$2.7M
NHLBI NIH HHS R01 HL157077
6 · The paper itself

Abstract

The piezoelectric effect has been widely observed in biological systems, and its applications in biomedical field are emerging. Recent advances of wearable and implantable biomedical devices bring promise as well as requirements for the piezoelectric materials building blocks. Owing to their biocompatibility, biosafety, and environmental sustainability, natural piezoelectric biomaterials are known as a promising candidate in this emerging field, with a potential to replace conventional piezoelectric ceramics and synthetic polymers. Herein, we provide a thorough review of recent progresses of research on five major types of piezoelectric biomaterials including amino acids, peptides, proteins, viruses, and polysaccharides. Our discussion focuses on their structure- and phase-related piezoelectric properties and fabrication strategies to achieve desired piezoelectric phases. We compare and analyze their piezoelectric performance and further introduce and comment on the approaches to improve their piezoelectric property. Representative biomedical applications of this group of functional biomaterials including energy harvesting, sensing, and tissue engineering are also discussed. We envision that molecular-level understanding of the piezoelectric effect, piezoelectric response improvement, and large-scale manufacturing are three main challenges as well as research and development opportunities in this promising interdisciplinary field.

Indexed as

Biocompatible MaterialsTissue EngineeringAmino AcidsPolymersProteinsAmino AcidsBiocompatible MaterialsPolymersProteinsamino acidsbiomedical devicesflexibilitynanogeneratornatural biomaterialspiezoelectricpolysaccharidesproteinssustainable materials

Identifiers

PMID36354375
PMCPMC10040090
OpenAlexW4308681347

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.