Evidence map›Paper›PMID 36354362›Full record

ArticleMicrobiology spectrum2022

Distinct Cytosolic Complexes Containing the Type III Secretion System ATPase Resolved by Three-Dimensional Single-Molecule Tracking in Live Yersinia enterocolitica.

Joshua R Prindle, Yibo Wang, Julian M Rocha, Andreas Diepold, Andreas Gahlmann

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Ultrafast Spectroscopy Reveals Slow Water Dynamics in Biocondensates.Journal of the American Chemical Society · 2023
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Joshua R PrindleDepartment of Chemistry, University of Virginiagrid.27755.32, Charlottesville, Virginia, USA.
Yibo WangDepartment of Chemistry, University of Virginiagrid.27755.32, Charlottesville, Virginia, USA.
Julian M RochaDepartment of Chemistry, University of Virginiagrid.27755.32, Charlottesville, Virginia, USA.
Andreas DiepoldMax Planck Institute for Terrestrial Microbiology, Marburg, Germany.
Andreas GahlmannDepartment of Chemistry, University of Virginiagrid.27755.32, Charlottesville, Virginia, USA.ORCID 0000-0001-7521-6787
University of Virginia · USMax Planck Institute for Terrestrial Microbiology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The membrane-embedded injectisome, the structural component of the virulence-associated type III secretion system (T3SS), is used by Gram-negative bacterial pathogens to inject species-specific effector proteins into eukaryotic host cells. The cytosolic injectisome proteins are required for export of effectors and display both stationary, injectisome-bound populations and freely diffusing cytosolic populations. How the cytosolic injectisome proteins interact with each other in the cytosol and associate with membrane-embedded injectisomes remains unclear. Here, we utilized three-dimensional (3D) single-molecule tracking to resolve distinct cytosolic complexes of injectisome proteins in living Yersinia enterocolitica cells. Tracking of the enhanced yellow fluorescent protein (eYFP)-labeled ATPase

Indexed as

Type III Secretion SystemsYersinia enterocoliticaAdenosine TriphosphatasesBacterial ProteinsCytosolProtein TransportAdenosine TriphosphatasesBacterial ProteinsType III Secretion Systemsbiophysicsphysiologyprotein-protein interactionssecretion systemssingle-molecule tracking

Identifiers

PMID36354362
PMCPMC9769973
OpenAlexW4308688893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.