Evidence map›Paper›PMID 36354318›Full record

ArticleJournal of bacteriology2022

Structural Differences in Complexes between the Master Regulator PrgX, Peptide Pheromones, and Operator Binding Sites Determine the Induction State for Conjugative Transfer of pCF10.

Takaya Segawa, Dawn A Manias, Gary M Dunny

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Takaya SegawaDepartment of Microbiology and Immunology, University of Minnesota Medical Schoolgrid.471402.4, Minneapolis, Minnesota, USA.
Dawn A ManiasDepartment of Microbiology and Immunology, University of Minnesota Medical Schoolgrid.471402.4, Minneapolis, Minnesota, USA.
Gary M DunnyDepartment of Microbiology and Immunology, University of Minnesota Medical Schoolgrid.471402.4, Minneapolis, Minnesota, USA.
University of Minnesota Medical Center · US

Funding

Enterococcal Sex pheromones: impact on antibiotic resistance transfer and ecology of the gastrointestinal tract.R35GM118079 · NIGMS · UNIVERSITY OF MINNESOTA · PI DUNNY, GARY M · 2016 to 2020
$2.1M
HHS | NIH | National Institute of General Medical Sciences (NIGMS) R35GM118079NIGMS NIH HHS R35 GM118079
6 · The paper itself

Abstract

Pheromone-inducible conjugation in the Enterococcus faecalis pCF10 system is regulated by the PrgX transcription factor through binding interactions at two operator binding sites (XBS1 and XBS2) upstream of the transcription start site of the

Indexed as

PeptidesTranscription FactorsBacterial ProteinsBinding SitesConjugation, GeneticEnterococcus faecalisMutationPheromonesPlasmidsBacterial ProteinsPeptidesPheromonesTranscription Factorsantibiotic resistancecell-cell signalinggene transfersex pheromone

Identifiers

PMID36354318
PMCPMC9764970
OpenAlexW4308679111

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.