Evidence map›Paper›PMID 36353932›Full record

ArticlePhysiological reports2022

Modulation of P2X

Biyang Xu, Oksana Nikolaienko, Vladislav Levchenko, Apurva Swapnil Choubey, Elena Isaeva, Alexander Staruschenko, Oleg Palygin

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Modulation of P2XPhysiological reports · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Biyang XuDepartment of Molecular Pharmacology and Physiology, University of South Florida, Tampa, Florida, USA.
Oksana NikolaienkoDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Vladislav LevchenkoDepartment of Molecular Pharmacology and Physiology, University of South Florida, Tampa, Florida, USA.
Apurva Swapnil ChoubeyDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Elena IsaevaDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Alexander StaruschenkoDepartment of Molecular Pharmacology and Physiology, University of South Florida, Tampa, Florida, USA.ORCID 0000-0002-5190-8356
Oleg PalyginDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.ORCID 0000-0002-3680-5527
Medical College of Wisconsin · USUniversity of South Florida · USMedical University of South Carolina · US

Funding

Renal ion channels in the control of blood pressureR35HL135749 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI STARUSCHENKO, ALEXANDER · 2017 to 2023
$3.6M
Role of basolateral K channels in renal salt handling and BP controlR01DK126720 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI PALYGIN, OLEG · 2021 to 2024
$1.5M
Transport and metabolism in the kidneyI01BX004024 · VA · JAMES A. HALEY VA MEDICAL CENTER · PI STARUSCHENKO, ALEXANDER · 2019 to 2025
–
BLRD VA I01 BX004024NHLBI NIH HHS R35 HL135749NIDDK NIH HHS R01 DK126720
6 · The paper itself

Abstract

Autosomal recessive polycystic kidney disease (ARPKD) is an inherited pathology caused mainly by mutations of the polycystic kidney and hepatic disease 1 (PKHD1) gene, which usually leads to end-stage renal disease. Previous studies suggested that the P2X purinoreceptor 4 (P2X

Indexed as

Polycystic Kidney, Autosomal RecessiveAdenosine TriphosphateAnimalsDisease Models, AnimalIvermectinRatsRats, Sprague-DawleyAdenosine TriphosphateIvermectin5-BDBDchronic treatmentivermectinkidneyPCK ratspolycystic kidney disease

Identifiers

PMID36353932
PMCPMC9647406
OpenAlexW4308772320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.