Evidence map›Paper›PMID 36353778›Full record

ArticleRespiration; international review of thoracic diseases2022

Nature and Trends in Personal Payments Made to the Respiratory Physicians by Pharmaceutical Companies in Japan between 2016 and 2019.

Anju Murayama, Momoko Hoshi, Hiroaki Saito, Sae Kamamoto, Manato Tanaka, Moe Kawashima, Hanano Mamada, Eiji Kusumi, Binaya Sapkota, Sunil Shrestha and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Respiration; international review of thoracic diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 3 countries.

Anju MurayamaMedical Governance Research Institute, Tokyo, Japan.
Momoko HoshiMedical Governance Research Institute, Tokyo, Japan.
Hiroaki SaitoDepartment of Gastroenterology, Sendai Kosei Hospital, Sendai, Japan.
Sae KamamotoMedical Governance Research Institute, Tokyo, Japan.
Manato TanakaMedical Governance Research Institute, Tokyo, Japan.
Moe KawashimaMedical Governance Research Institute, Tokyo, Japan.
Hanano MamadaMedical Governance Research Institute, Tokyo, Japan.
Eiji KusumiDepartment of Internal Medicine, Navitas Clinic Shinjuku, Tokyo, Japan.
Binaya SapkotaNobel College Faculty of Health Sciences, Affiliated to Pokhara University, Kathmandu, Nepal.
Sunil ShresthaSchool of Pharmacy, Monash University Malaysia, Subang Jaya, Malaysia.
Rajeev ShresthaDepartment of Pharmacy, District Hospital Lamjung, Besisahar, Nepal.
Divya BhandariMedical Governance Research Institute, Tokyo, Japan.
Toyoaki SawanoDepartment of Surgery, Jyoban Hospital of Tokiwa Foundation, Iwaki, Japan.
Erika YamashitaMedical Governance Research Institute, Tokyo, Japan.
Tetsuya TanimotoDepartment of Internal Medicine, Navitas Clinic, Tachikawa, Japan.
Akihiko OzakiMedical Governance Research Institute, Tokyo, Japan.
Medical Governance Research Institute · JPJyoban Hospital of Tokiwa Foundation · JPTohoku University · JPDhulikhel Hospital · NPFukushima Medical University · JPMonash University Malaysia · MYPokhara University · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFinancial relationships between healthcare professionals and pharmaceutical companies have historically caused conflicts of interest and unduly influenced patient care. However, little was known about such relationship and its effect in clinical practice among specialists in respiratory medicine.

methodsBased on the retrospective analysis of payment data made available by all 92 pharmaceutical companies in Japan, this study evaluated the magnitude and trend of financial relationships between all board-certified Japanese respiratory specialists and pharmaceutical companies between 2016 and 2019. Magnitude and prevalence of payments for specialists were analyzed descriptively. The payment trends were assessed using the generalized estimating equations for the payment per specialist and the number of specialists with payments.

resultsAmong all 7,114 respiratory specialists certified as of August 2021, 4,413 (62.0%) received a total of USD 53,547,391 and 74,195 counts from 72 (78.3%) pharmaceutical companies between 2016 and 2019. The median (interquartile range) 4-year combined payment values per specialist were USD 2,210 (USD 715-8,178). At maximum, one specialist received USD 495,332 personal payments over the 4 years. Both payments per specialist and number of specialists with payments significantly increased during the 4-year period, with 7.8% (95% CI: 5.5-9.8; p < 0.001) in payments and 1.5% (95% CI: 0.61-2.4; p = 0.001) in number of specialists with payments, respectively.

conclusionThe majority of respiratory specialists had increasingly received more personal payments from pharmaceutical companies for the reimbursement of lecturing, consulting, and writing between 2016 and 2019. These increasing financial relationships with pharmaceutical companies might cause conflicts of interest among respiratory physicians.

Indexed as

Conflict of InterestDrug IndustryHumansJapanPharmaceutical PreparationsPulmonologistsRetrospective StudiesPharmaceutical PreparationsConflict of interestEthicsHealth policyIndustry paymentJapanJapanese respiratory societyPhysician paymentRespiratory specialist

Identifiers

PMID36353778
PMCPMC9811425
OpenAlexW4308684616

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.