Trial reportRespiration; international review of thoracic diseases2022
Comparison of Lung, Lobe, and Airway Volumes between Supine and Upright Computed Tomography and Their Correlation with Pulmonary Function Test in Patients with Chronic Obstructive Pulmonary Disease.
Trial report in Respiration; international review of thoracic diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Chest CT in the evaluation of chronic obstructive pulmonary disease: recommendations of Asian Society of Thoracic Radiology.The British journal of radiology · 2026Guideline
- Thoracic posture-related morphological changes in patients with pectus excavatum versus healthy controls.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024Trial
- Comparison of biomechanical assessment between upright and supine inspiratory-expiratory area-detector CT in progressive pulmonary fibrosis.European radiology experimental · 2026Article
- Complementary assessment of cardiopulmonary morphometric changes in COPD using 3D multidetector computed tomography: relationship with functional indices.BMC pulmonary medicine · 2026Article
- Upright multidetector CT with 320-row gantry: a technical innovation providing insights into human anatomy under gravity and potential clinical implications.The British journal of radiology · 2025Article
- Recent trends in scientific research in chest radiology: What to do or not to do? That is the critical question in research.Japanese journal of radiology · 2025Review
- Iodine concentration in the lung parenchyma in relation to different inspiratory depths during CT pulmonary angiography.The British journal of radiology · 2025Article
- Differences in lung attenuation gradients between supine and standing positions in healthy participants on conventional/supine and upright computed tomography.Scientific reports · 2024Article
- Impact of rapid iodine contrast agent infusion on tracheal diameter and lung volume in CT pulmonary angiography measured with deep learning-based algorithm.Japanese journal of radiology · 2024Article
- Upright CT-based evaluation of the effects of posture on skull-base reconstruction after endoscopic endonasal surgery.Scientific reports · 2024Article
- Effects of Intravenous Infusion of Iodine Contrast Media on the Tracheal Diameter and Lung Volume Measured with Deep Learning-Based Algorithm.Journal of imaging informatics in medicine · 2024Article
- Exploration of postural effects on the external jugular and diploic venous system using upright computed tomography scanning.Neuroradiology · 2024Article
- Estimating right atrial pressure using upright computed tomography in patients with heart failure.European radiology · 2023Article
- A new method for evaluating lung volume: AI-3D reconstruction.Frontiers in physiology · 2023Article
- Comparison of inspiratory and expiratory airway volumes and luminal areas among standing, sitting, and supine positions using upright and conventional CT.Scientific reports · 2022Article
- Differences in lung and lobe volumes between supine and upright computed tomography in patients with idiopathic lung fibrosis.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCorrelations between upright CT and pulmonary function test (PFT) measurements, and differences in lung/lobe/airway volumes between supine and standing positions in patients with chronic obstructive pulmonary disease (COPD) remain unknown.
objectivesThe study aimed to evaluate correlations between lung/airway volumes on both supine and upright CT and PFT measurements in patients with COPD, and compare CT-based inspiratory/expiratory lung/lobe/airway volumes between the two positions.
methodsForty-eight patients with COPD underwent both conventional supine and upright CT in a randomized order during inspiration and expiration breath-holds, and PFTs within 2 h. We measured the lung/lobe/airway volumes on both CT.
resultsThe correlation coefficients between total lung volumes on inspiratory CT in supine/standing position and PFT total lung capacity and vital capacity were 0.887/0.920 and 0.711/0.781, respectively; between total lung volumes on expiratory CT in supine/standing position and PFT functional residual capacity and residual volume, 0.676/0.744 and 0.713/0.739, respectively; and between airway volume on inspiratory CT in supine/standing position and PFT forced expiratory volume in 1 s, 0.471/0.524, respectively. Inspiratory/expiratory bilateral upper and right lower lobe, bilateral lung, and airway volumes were significantly higher in the standing than supine position (3.6-21.2% increases, all p < 0.05); however, inspiratory/expiratory right middle lobe volumes were significantly lower in the standing position (4.6%/15.9% decreases, respectively, both p < 0.001).
conclusionsUpright CT-based volumes were more correlated with PFT measurements than supine CT-based volumes in patients with COPD. Unlike other lobes and airway, inspiratory/expiratory right middle lobe volumes were significantly lower in the standing than supine position.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.