ArticleJournal of oral biology and craniofacial research
The evaluation of the effects of natural zeolite (Clinoptilolite) in diabetic rats on bone healing in dental extracting socket.
Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Effects of Myroxylon pereirae, Phenytoin, and Clinoptilolite After Pharyngocutaneous Fistula: An Experimental Animal Model.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- PMA-Zeolite: Chemistry and Diverse Medical Applications.Journal of functional biomaterials · 2024Review
- Application of Zeolites and Zeolitic Imidazolate Frameworks in Dentistry-A Narrative Review.Nanomaterials (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: The fact that clinoptilolite reserves are abundant and economical in the world, its toxic effects are not observed in clinical studies in humans and animals, and it has superior physical properties suggests that clinoptilolite may be an easily accessible product for the healing of tooth extraction wounds. The aim of the study was to evaluate the effects of cliniotilolite on bone tissue healing and bone formation in the extraction socket in experimentally diabetic rats by micro-CT analysis. Materials and methods: 36 male Wistar Albino rats were divided into 3 main groups as Healthy Control, Diabetes Control and Diabetes + Clinoptilolite. Afterwards, these groups were divided into 2 subgroups to be sacrificed on the 14th and 28th days, and each subgroup had 6 rats (n = 6). At the 14th and 28th days, the rats were sacrificed and the effects of clinoptilolite on bone tissue healing and bone formation in the alveolar socket were evaluated by micro-CT analysis. Results: According to the statistical analysis results, the difference between the groups in terms of bone volume, bone surface to bone volume, trabecular thickness and hounsfield units values, which are the parameters of the 14th day groups, was statistically significant (p < 0.05). Among the parameters of the 28th day groups, only the hounsfield units value was statistically significant (p < 0.05). Conclusion: The results of the study show that clinoptilolite can contribute to the healing of extraction wounds and bone formation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.