Evidence map›Paper›PMID 36353644›Full record

ArticleFrontiers in immunology2022

Unbalanced Arginine pathway and altered maturation of pleural macrophages in Th2-deficient mice during

Estelle Remion, Joséphine Gal, Soraya Chaouch, Jules Rodrigues, Nathaly Lhermitte-Vallarino, Joy Alonso, Linda Kohl, Marc P Hübner, Frédéric Fercoq, Coralie Martin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Estelle RemionUnit Communication Molecules and Adaptation of Micro-organisms (MCAM, UMR 7245), Team Parasites and Free Protistes, Muséum National d'Histoire Naturelle, CNRS; CP52, 61 rue Buffon, 75005 Paris, France.
Joséphine GalUnit Communication Molecules and Adaptation of Micro-organisms (MCAM, UMR 7245), Team Parasites and Free Protistes, Muséum National d'Histoire Naturelle, CNRS; CP52, 61 rue Buffon, 75005 Paris, France.
Soraya ChaouchUnit Communication Molecules and Adaptation of Micro-organisms (MCAM, UMR 7245), Team Parasites and Free Protistes, Muséum National d'Histoire Naturelle, CNRS; CP52, 61 rue Buffon, 75005 Paris, France.
Jules RodriguesUnit Communication Molecules and Adaptation of Micro-organisms (MCAM, UMR 7245), Team Parasites and Free Protistes, Muséum National d'Histoire Naturelle, CNRS; CP52, 61 rue Buffon, 75005 Paris, France.
Nathaly Lhermitte-VallarinoUnit Communication Molecules and Adaptation of Micro-organisms (MCAM, UMR 7245), Team Parasites and Free Protistes, Muséum National d'Histoire Naturelle, CNRS; CP52, 61 rue Buffon, 75005 Paris, France.
Joy AlonsoUnit Communication Molecules and Adaptation of Micro-organisms (MCAM, UMR 7245), Team Parasites and Free Protistes, Muséum National d'Histoire Naturelle, CNRS; CP52, 61 rue Buffon, 75005 Paris, France.
Linda KohlUnit Communication Molecules and Adaptation of Micro-organisms (MCAM, UMR 7245), Team Parasites and Free Protistes, Muséum National d'Histoire Naturelle, CNRS; CP52, 61 rue Buffon, 75005 Paris, France.
Marc P HübnerInstitute for Medical Microbiology, Immunology & Parasitology (IMMIP), University Hospital of Bonn, Bonn, Germany.
Frédéric FercoqUnit Communication Molecules and Adaptation of Micro-organisms (MCAM, UMR 7245), Team Parasites and Free Protistes, Muséum National d'Histoire Naturelle, CNRS; CP52, 61 rue Buffon, 75005 Paris, France.
Coralie MartinUnit Communication Molecules and Adaptation of Micro-organisms (MCAM, UMR 7245), Team Parasites and Free Protistes, Muséum National d'Histoire Naturelle, CNRS; CP52, 61 rue Buffon, 75005 Paris, France.
Molécules de Communication et Adaptation des Micro-organismes · FRUniversity Hospital Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Filarial parasites are tissue dwelling worms transmitted by hematophagous vectors. Understanding the mechanisms regulating microfilariae (the parasite offspring) development is a prerequisite for controlling transmission in filarial infections. Th2 immune responses are key for building efficient anti-parasite responses but have been shown to also lead to detrimental tissue damage in the presence of microfilariae.

Indexed as

FilariasisFilarioideaAnimalsArginineInterleukin-5MacrophagesMiceMice, Inbred BALB CMicrofilariaeTh2 CellsArginineInterleukin-5filariasislungmacrophagemicrofilarianematodeparasitepleura

Identifiers

PMID36353644
PMCPMC9637854
OpenAlexW4307272071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.