ReviewFrontiers in physiology2022
Premature atrial contractions: A predictor of atrial fibrillation and a relevant marker of atrial cardiomyopathy.
Review in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 14 citations in OpenAlex.
- Premature Atrial Contractions as a Marker of Atrial Cardiopathy: A Revised Analysis of the ARCADIA Randomized Trial.Journal of cardiovascular electrophysiology · 2025Trial
- Excessive Supraventricular Ectopic Activity in Patients With Acute Ischemic Stroke Is Associated With Atrial Fibrillation Detection Within 24 Months After Stroke: A Predefined Analysis of the MonDAFIS Study.Journal of the American Heart Association · 2025Trial
- Determinants and prognostic value of atrial and ventricular ectopic burden in adults without structural heart disease.European heart journal open · 2026Article
- Atrial Cardiomyopathy: Pathophysiology, Diagnostic Approaches, and Prognostic Implications-A Narrative Review.Journal of clinical medicine · 2026Review
- Atrial cardiomyopathy as a multidomain disease: longitudinal evidence for autonomic remodelling.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- Ambulatory Holter Findings in Patients with Palpitations and Structurally Normal Heart: A Prospective Study of the Prevalence and Patterns of Ventricular and Supraventricular Arrhythmias.Journal of clinical medicine · 2026Article
- Efficacy evaluation of Wenxin Keli in treating anthracycline-induced atrial arrhythmias (WARMA study): protocol for a multicenter, randomized, double-blind, placebo-controlled clinical trial.Frontiers in cardiovascular medicine · 2026Article
- Artificial intelligence for prediction of atrial fibrillation in the stroke unit: a retrospective derivation validation cohort study.EBioMedicine · 2025Article
- Assessing heart rate fragmentation to predict atrial fibrillation in the general population aged 65: the PROOF-AF study.European heart journal open · 2025Article
- Arterial Stiffness and Markers of Atrial Myopathy.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2025Article
- Left atrial anomalous bands associated with arrhythmia detected by computed tomography during coronary CT angiography: a case series.American journal of translational research · 2025Article
- Atrial Fibrillation Already Known Versus Detected After Stroke: Same Battle?Journal of the American Heart Association · 2024Article
- Prediction of underlying atrial fibrillation in patients with a cryptogenic stroke: results from the NOR-FIB Study.Journal of neurology · 2023Observational
- Electrophysiological basis of cardiac arrhythmia in a mouse model of myotonic dystrophy type 1.Frontiers in physiology · 2023Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An increased burden of premature atrial contractions (PACs) has long been considered a benign phenomenon. However, strong evidence of their involvement in the occurrence of atrial fibrillation (AF), ischemic stroke, and excess mortality suggests the need for management. The central question to be resolved is whether increased ectopic atrial rhythm is only a predictor of AF or whether it is a marker of atrial cardiomyopathy and therefore of ischemic stroke. After reviewing the pathophysiology of PACs and its impact on patient prognosis, this mini-review proposes to 1) detail the physiological and clinical elements linking PACs and AF, 2) present the evidence in favor of supraventricular ectopic activity as a marker of cardiomyopathy, and 3) outline the current limitations of this concept and the potential future clinical implications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.