ArticleForensic sciences research2022
MiR-711 and miR-183-3p as potential markers for vital reaction of burned skin.
Article in Forensic sciences research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- State-of-the-Art on Wound Vitality Evaluation: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Melatonin attenuates reproductive toxicity of prothioconazole and its metabolite via spermatogenesis and oxidative stress.Communications biology · 2026Article
- Therapeutic Potential of Modulating Gene-MicroRNA Crosstalk in Burn Injury.International journal of molecular sciences · 2025Review
- Research progress and potential application of microRNA and other non-coding RNAs in forensic medicine.International journal of legal medicine · 2024Review
- The potential of using non-coding RNAs in forensic science applications.Forensic sciences research · 2023Review
- Gut microbiota from sigma-1 receptor knockout mice induces depression-like behaviors and modulates the cAMP/CREB/BDNF signaling pathway.Frontiers in microbiology · 2023Article
- Cause of Death in Charred Bodies: Reflections and Operational Insights Based on a Large Cases Study.Diagnostics (Basel, Switzerland) · 2022Article
- Screening criteria of mRNA indicators for wound age estimation.Forensic sciences research · 2022Article
- Luteolin Ameliorates Methamphetamine-Induced Podocyte Pathology by Inhibiting Tau Phosphorylation in Mice.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- MiRNAs as New Tools in Lesion Vitality Evaluation: A Systematic Review and Their Forensic Applications.Biomedicines · 2021Review
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In forensic practice, the identification of antemortem burns and postmortem burns is of the utmost importance. Reports from previous studies have shown that miRNAs, with lengths stretching over 18-25 nucleotides, are highly stable and resistant to degradation. However, there has been little research into the application of miRNAs in identifying antemortem and postmortem burns. This study compared the expression of miR-711 and miR-183-3p levels in mouse and postmortem human burned skins using RT-qPCR assay. RT-qPCR examination of burned mouse skins showed that increased miR-711 and miR-183-3p expression in comparison to intact skin tissues. The increased expressions of these two miRNAs were observed until 120 h after death in burned mouse skins, whereas no significant changes were found in postmortem burned skins. In human burned skins, the increased levels of these two miRNAs at 48 h following autopsy occurred in 19 of 26 subjects, which appeared to be related to the severity of the burn. These findings suggest that miR-711 and miR-183-3p may act as biomarkers for vital reaction of skin burn.Key pointsThis study investigated miR-711 and miR-183-3p levels in mouse and postmortem human burned skins using RT-qPCR.Increased miR-711 and miR-183-3p levels were observed in burned mouse skins.The increased expressions of these two miRNAs were observed until 120 h after death in burned mouse skin.The increased levels of these two miRNAs were observed until 48 h after autopsy in 19 of 26 forensic cases, which appeared to be related to the severity of the burn.
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