Evidence map›Paper›PMID 36353142›Full record

ArticleFrontiers in chemistry2022

Manganese-based Prussian blue nanoparticles inhibit tumor proliferation and migration

Shanshi Tong, Zhilong Yu, Fang Yin, Qilin Yang, Juhang Chu, Luyao Huang, Wenxue Gao, Mingping Qian

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Shanshi TongDepartment of General Surgery, Shanghai tenth People's Hospital, Shanghai, China.
Zhilong YuDepartment of Gastroenterological Surgery, Peking University People's Hospital, Beijing, China.
Fang YinShanghai Engineering Technology Research Center for the Functional Development of Human Intestinal Flora, Shanghai tenth People's Hospital, Shanghai, China.
Qilin YangDepartment of General Surgery, Shanghai tenth People's Hospital, Shanghai, China.
Juhang ChuSchool of Medicine, Tongji University, Shanghai, China.
Luyao HuangDepartment of General Surgery, Shanghai tenth People's Hospital, Shanghai, China.
Wenxue GaoClinical Research Management Office, Shanghai tenth People's Hospital, Shanghai, China.
Mingping QianDepartment of General Surgery, Shanghai tenth People's Hospital, Shanghai, China.
Shanghai Tenth People's Hospital · CNPeking University · CNShanghai Jiao Tong University · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer (PC) is one of the deadliest gastrointestinal malignancies. Advances in molecular biology and surgery have significantly improved survival rates for other tumors in recent decades, but clinical outcomes for PC remained relatively unchanged. Chemodynamic therapy (CDT) and Photothermal therapy (PTT) represent an efficient and relatively safe cancer treatment modality. Here, we synthesized Mn-doped Prussian blue nanoparticles (MnPB NPs) through a simple and mild method, which have a high loading capacity for drugs and excellent CDT/PTT effect. Cell line experiments

Indexed as

chemodynamic therapyMnPB NPspancreatic cancerphotothermal therapythe MAPK pathway

Identifiers

PMID36353142
PMCPMC9638070
OpenAlexW4307274157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.