Evidence map›Paper›PMID 36353120›Full record

ArticlemicroPublication biology2022

Mutation of the H12-helix of α-tubulin/MEC-12 disrupts the localization of neuronal mitochondria.

Jean-Sébastien Teoh, Samiksha Dhananjay, Brent Neumann

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in microPublication biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jean-Sébastien Teoh *Neuroscience Program, Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, Monash University, Melbourne VIC 3800 Australia.
Samiksha Dhananjay *Neuroscience Program, Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, Monash University, Melbourne VIC 3800 Australia.
Brent NeumannNeuroscience Program, Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, Monash University, Melbourne VIC 3800 Australia.
Discovery Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microtubules are essential components of the cytoskeleton that allow bi-lateral neuronal transport. Correct regulation of these complex intracellular transport processes is central to neuronal function. However, despite major advancements in our knowledge, we still lack a complete understanding on how neuronal transport is regulated. Here, we provide further evidence for the importance of the highly conserved N-terminal H12-helix of α-tubulin. We show that a mutation in this region results in the mistargeting of axonal mitochondria in

Identifiers

PMID36353120
PMCPMC9638805
OpenAlexW4308770146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.