Evidence map›Paper›PMID 36353107›Full record

ArticleFrontiers in genetics2022

Novel IKZF3 transcriptomic signature correlates with positive outcomes of skin cutaneous melanoma: A pan-cancer analysis.

Lin-Kai Yang, Can-Xiang Lin, Sheng-Hong Li, Jia-Ji Liang, Li-Ling Xiao, Guang-Hui Xie, Hong-Wei Liu, Xuan Liao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lin-Kai YangDepartment of Plastic Surgery, The First Affiliated Hospital of Jinan University, Innovative Technology Research Institute of Tissue Repair and Registration, Key Laboratory of Regenerative Medicine, Ministry of Education, Guangzhou, Guangdong Province, China.
Can-Xiang LinDepartment of Plastic Surgery, The First Affiliated Hospital of Jinan University, Innovative Technology Research Institute of Tissue Repair and Registration, Key Laboratory of Regenerative Medicine, Ministry of Education, Guangzhou, Guangdong Province, China.
Sheng-Hong LiDepartment of Plastic Surgery, The First Affiliated Hospital of Jinan University, Innovative Technology Research Institute of Tissue Repair and Registration, Key Laboratory of Regenerative Medicine, Ministry of Education, Guangzhou, Guangdong Province, China.
Jia-Ji LiangDepartment of Plastic Surgery, The First Affiliated Hospital of Jinan University, Innovative Technology Research Institute of Tissue Repair and Registration, Key Laboratory of Regenerative Medicine, Ministry of Education, Guangzhou, Guangdong Province, China.
Li-Ling XiaoDepartment of Plastic Surgery, The First Affiliated Hospital of Jinan University, Innovative Technology Research Institute of Tissue Repair and Registration, Key Laboratory of Regenerative Medicine, Ministry of Education, Guangzhou, Guangdong Province, China.
Guang-Hui XieDepartment of Plastic Surgery, The First Affiliated Hospital of Jinan University, Innovative Technology Research Institute of Tissue Repair and Registration, Key Laboratory of Regenerative Medicine, Ministry of Education, Guangzhou, Guangdong Province, China.
Hong-Wei LiuDepartment of Plastic Surgery, The First Affiliated Hospital of Jinan University, Innovative Technology Research Institute of Tissue Repair and Registration, Key Laboratory of Regenerative Medicine, Ministry of Education, Guangzhou, Guangdong Province, China.
Xuan LiaoDepartment of Plastic Surgery, The First Affiliated Hospital of Jinan University, Innovative Technology Research Institute of Tissue Repair and Registration, Key Laboratory of Regenerative Medicine, Ministry of Education, Guangzhou, Guangdong Province, China.
First Affiliated Hospital of Jinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the potential relationship between Ikaros family genes and skin cutaneous melanoma (SKCM), we undertook a pan-cancer analysis of the transcriptional signature and clinical data of melanoma through multiple databases. First, 10,327 transcriptomic samples from different cancers were included to determine the overall characteristics and clinical prognoses associated with Ikaros gene expression across cancer types. Second, differentially expressed genes analysis, prognostic evaluation, and gene set enrichment analysis were employed to investigate the role of Ikaros (

Indexed as

ikaros family genesimmune infiltrationimmunotherapy biomarkerpan-cancer analysisSKCM

Identifiers

PMID36353107
PMCPMC9638148
OpenAlexW4307160340

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.